In vitro reconstitution of meiotic DNA double-strand breaks: A long-standing challenge solved
In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks ...
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童明汉组合作实现在体外重构减数分裂DSB形成
减数分裂是存在于有性生殖生物中的特殊细胞分裂方式，为有性生殖的基础。同源重组是减数分裂中最重要的生物学事件，它不仅使来自亲本双方的遗传物质发生交换，增加了物种遗传的多样性；而且还能让同源染色体之间建立物理连接，以确保它们的精确分离，维持染色体数量的恒 ...
Nature4 年
Meiotic timelines for humans
How is the same process responsible for genetic recombination and diversity also the cause of aneuploidy? Understanding the steps of meiosis is essential to learning how errors occur.
EurekAlert!1 天
Researchers reconstitute meiotic double-strand break formation in vitro
Researchers led by Prof. TONG Minghan from the Center for Excellence in Molecular Cell Science of the Chinese Academy of Sciences, collaborating with Prof. HUANG Ying from Xinhua Hospital, Shanghai ...
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Scientists Recreate Meiotic Breaks In Vitro
In a study published in Nature, researchers led by Prof. TONG Minghan from the Center for Excellence in Molecular Cell Science (Shanghai Institute of ...