Researchers led by Prof. TONG Minghan from the Center for Excellence in Molecular Cell Science of the Chinese Academy of Sciences, collaborating with Prof. HUANG Ying from Xinhua Hospital, Shanghai ...

In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks ...

In a study published in Nature, researchers led by Prof. TONG Minghan from the Center for Excellence in Molecular Cell Science (Shanghai Institute of ...

减数分裂是存在于有性生殖生物中的特殊细胞分裂方式，为有性生殖的基础。同源重组是减数分裂中最重要的生物学事件，它不仅使来自亲本双方的遗传物质发生交换，增加了物种遗传的多样性；而且还能让同源染色体之间建立物理连接，以确保它们的精确分离，维持染色体数量的恒 ...

为了解决体外重构减数分裂DSB形成这一难题，童明汉课题组利用体外蛋白表达纯化系统成功获得了SPO11-TOP6BL复合体，并首次在体外重现其切割DNA双链的活性。之后，与新华医院黄旲团队合作，采用凝胶过滤层析、交联质谱、Pull ...

（通讯员 陶敏）2024年2月29日，我校刘少军院士团队联合西南大学、中科院水生所有关人员在Molecular Biology and evolution杂志上发表了题为“Formation of different polyploids ...

为解决体外重构减数分裂 DSB 形成这一难题，童明汉课题组利用体外蛋白表达纯化系统获得 SPO11-TOP6BL 复合体，并首次在体外重现其切割 DNA 双链的活性。随后，童明汉课题组与黄旲团队合作，采用凝胶过滤层析、交联质谱、 Pull Down 等方法，探讨了 SPO11-TOP6BL ...

A team of physicists, materials scientists and engineers affiliated with several institutions in China, working with a ...

Researchers have used artificial intelligence (AI) to design brand-new enzymes that can go through multi-step reactions, a ...