Medical Xpress25 天
Light-activated compound offers hope for overcoming drug resistance in cancer treatment
To combat this autophagy, the research team designed a photoreactive compound that integrates morpholine and iridium. Morpholine selectively targets cell lysosomes, the organelles where autophagy ...
C&EN26 天
Discovery and Optimization of a Series of Novel Morpholine-Containing USP1 Inhibitors
Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, P. R. China State Key Laboratory of Chemical Biology, ...