More information: Elana Bryan et al, Nucleosomal asymmetry shapes histone mark binding and promotes poising at bivalent domains, Molecular Cell (2024). DOI: 10.1016/j.molcel.2024.12.002 Journal ...

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This valuable study is a detailed investigation of how chromatin structure influences replication origin function in yeast ribosomal DNA, with a focus on the role of the histone deacetylase Sir2 and ...

ATP-dependent chromatin remodelling proteins represent a diverse family of proteins that share ATPase domains that are adapted to regulate protein–DNA interactions. Here, we present structures of the ...