The EASI-ORC pipeline provides a robust toolset for the analysis of fluorescent microscopy images of yeast for mRNA-organelle colocalization. An accompanying step-by-step user guide allows for ...

Moreover, these proteins were unable to arrive at their proper destination—a cellular organelle in which they are supposed to function—and were found instead inside another organelle that handles ...

Mitochondria are cytoplasmic organelles found in most eukaryotic cells. They are formed from an outer membrane, a highly invaginated inner membrane containing cristae, and a matrix. Mitochondria ...

Invaginations of the nuclear membrane occur in different shapes, sizes, and compositions. Part of these pleiomorphic invaginations make up the nucleoplasmic reticulum (NR), while others are merely ...

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China College of Materials Science and Optoelectronic ...

Although high-throughput techniques facilitate identification of novel contact sites (e.g., organelle-organelle and organelle-vesicle interactions), little is known about their impact on cellular ...

Furthermore, MAP7 recruits kinesin-1 dynamically to microtubules, leading to alterations in organelle transport behaviors, particularly pause/speed switching. As MAP7 is localized to branch sites, our ...