Tyrosine kinase 2 (TYK2) critically regulates tau levels and aggregation by phosphorylating tau’s tyrosine 29. Partial inhibition of TYK2 mitigates tau pathologies in cells and mice ...

Researchers have revealed the role of enzyme TYK2 in the aggregation of tau proteins, which contributes to Alzheimer’s ...

These CENP-A proteins ensure that divided genetic information is kept intact during mitosis.

Genetically editing sugar-regulating genes increases tomato sweetness, without affecting yield or size. The findings break a ...

Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, Zhangjiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai 200240, China ...

The framework “offers a transformative approach in the field of cell-free organelle-based therapy, particularly focusing on the use of neural stem cell-derived oxidative phosphorylating ...

Researchers from IACS Kolkata have identified TDP1 as a potential target for cancer therapy, offering hope for overcoming resistance to existing treatments. By inhibiting TDP1 and CDK1, the new ...

Dramatic change in chromosomal DNA morphology between interphase and mitosis is a defining features of the eukaryotic cell cycle. Two types of enzymes, namely cohesin and condensin confer the topology ...

However, kinetochores initially bind to microtubules indiscriminately, resulting in errors that must be corrected. While the Aurora B protein kinase destabilizes low-tension attachments by ...