The following is a summary of “Cross-trait GWAS in COVID-19 and systemic sclerosis reveals novel genes implicated in fibrotic ...

The following is a summary of “Causal relationship between major depressive disorder, anxiety disorder and constipation: a ...

In 2019 an international team of researchers identified 109 genes that were associated in different combinations with eight different psychiatric disorders, including autism, ADHD, schizophrenia, ...

Cochran’s Q statistic was used to quantify the heterogeneity of instrumental variables (IVs), and the MR Egger intercept test was used to assess the pleiotropy of IVs. Conclusion: We discovered that ...

Although other robust MR methods did not manifest a significant association between periodontitis and endometriosis of the pelvic peritoneum, the sensitivity analysis showed no potential horizontal ...

China: A recent study published in the International Journal of Women's Health has shed light on the potential causal ...

Pharmaceutical ads are difficult to avoid in American television programming and a growing number of them promote a class of medications called JAK inhibitors, using an acronym that assumes the ...

Antagonistic Pleiotropy This theory posits that some genes that are beneficial in early life for reproductive success may have harmful effects in later life. For example, genes that enhance immune ...

The findings have been reported in Cell. "Pleiotropy was traditionally viewed as a challenge because it complicates the classification of psychiatric disorders," said senior study author Hyejung Won, ...

Researchers have identified specific gene variants that have significant impacts on brain development and are shared across ...