Different from other medications, a prodrug remains inactive until it encounters a specific circumstance in the body that activates it. One of the major benefits of using a prodrug is that it ...

"Our team has created a targeted prodrug (a compound which metabolizes inside the body into a pharmacologically active drug), ...

The grant focuses on a promising new prodrug, CTT2274, that targets Prostate-Specific Membrane Antigen (PSMA) on prostate cancer and is designed to release a toxic drug, MMAE, within the cell that ...

Peer-reviewed publication features positive results from multiple ascending dose (MAD) portion of Phase 1 MBX 2109 study in ...

Memorial Sloan Kettering Cancer Center-led researchers have identified a small molecule called gliocidin that kills ...

And how does that affect its activity? Dr. Sabatine: Clopidogrel is a prodrug and it needs to be activated through sequential oxidative steps in the liver (Slide 1). There is another pathway where ...

Cancer Targeted Technology LLC has been awarded the phase I portion ($400,000) of a fast track phase I/II ($2.4 million) Small Business Innovation Research (SBIR) grant by the National Cancer ...

The company’s lead drug candidate, MIV-818, is a liver cancer targeted prodrug that Medivir is looking to develop alone in the USA and the EU and through partnerships elsewhere. Swedish ...

MBX Biosciences (MBX) announced the publication of a peer-reviewed article highlighting results from the Phase 1 study of MBX 2109, the ...

The FDA has endorsed CaaMTech's approach to handling "functional unblinding" in its CT-4201 psilocin prodrug trials. This approval paves the way for CT-4201’s development and progress in ...

MBX Biosciences, Inc. (Nasdaq: MBX), a clinical-stage biopharmaceutical company focused on the discovery and development of novel precision peptide therapies for the ...