Background Early-life inflammation has long been recognised as a key pathophysiological process in the evolution of cystic fibrosis (CF) lung disease. Despite this, no CF-specific anti-inflammatory ...

Background: In adults, viral causes of community-acquired pneumonia (CAP) are poorly characterised. The aims of this study were to characterise the viral aetiology of CAP in adults by using an ...

Interstitial Lung Disease Center, Division of Pulmonary Sciences and Critical Care Medicine, National Jewish Medical and Research Center and University of Colorado Health Sciences Center, Denver, ...

BACKGROUND An obstructive defect is usual in bronchiectasis, but the pathophysiological basis of airflow obstruction remains uncertain. High resolution computed tomographic (CT) scanning now allows ...

2 Pediatric Respiratory and Allergy Units, “Arrixaca” University Children's Hospital, University of Murcia and CIBER of Epidemiology and Public Health (CIBERSP), Murcia, Spain 3 Division of Community ...

1 Respiratory Medicine, Royal Infirmary of Edinburgh and University of Edinburgh, Edinburgh, UK 2 Department of Respiratory Medicine, University Hospitals Birmingham NHS Foundation Trust (Queen ...

1 Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan 2 Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, ...

Correspondence to Michael A Mitchell, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; MichaelA.Mitchell{at}lhsc.on.ca Background Pleural ...

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Background Severe obesity causes respiratory morbidity and mortality. The impact of obesity on the mechanics of breathing is not fully understood. Conclusions Obese subjects have markedly increased ...

Epidemiology Unit, Tuberculosis Research Centre, Chennai, Indian Council of Medical Research, India Correspondence to: Dr C Kolappan, Epidemiology Unit, Tuberculosis Research Centre, Mayor V R ...

1 Department of Medicine, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Medical Center, Columbus, Ohio, USA Background The mechanisms underlying chronic obstructive ...