BACKGROUND An obstructive defect is usual in bronchiectasis, but the pathophysiological basis of airflow obstruction remains uncertain. High resolution computed tomographic (CT) scanning now allows ...

2 Pediatric Respiratory and Allergy Units, “Arrixaca” University Children's Hospital, University of Murcia and CIBER of Epidemiology and Public Health (CIBERSP), Murcia, Spain 3 Division of Community ...

British Thoracic Society Standards of Care Committee in collaboration with and endorsed by the Royal College of Physicians of London, Royal College of General Practitioners, British Geriatrics Society ...

Background: In adults, viral causes of community-acquired pneumonia (CAP) are poorly characterised. The aims of this study were to characterise the viral aetiology of CAP in adults by using an ...

3 Department of Medicine, Columbia University, New York, New York, USA 4 Center for Genomics and Personalized Medicine Research, Wake Forest University, Winston-Salem, New York, USA 5 Department of ...

1 Department of Medicine, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Medical Center, Columbus, Ohio, USA Background The mechanisms underlying chronic obstructive ...

1 Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, P O Box 913, Dunedin, New Zealand 2 Department of Paediatric Respiratory Medicine, Erasmus MC - Sophia ...

Background Vitamin A, an essential micronutrient obtained through the diet, plays a crucial role in lung development and contributes to lung regeneration. We aimed to investigate its effect on adult ...

Background Early-life inflammation has long been recognised as a key pathophysiological process in the evolution of cystic fibrosis (CF) lung disease. Despite this, no CF-specific anti-inflammatory ...

Background The Global Obstructive Lung Disease (GOLD) 2011 revision recommends the multidimensional assessment of COPD including comorbidities and has developed a ...

Section of Thoracic Medicine, Institute of Medicine, University of Bergen, Norway Background: Early life development may influence subsequent respiratory morbidity. The impact of factors determined in ...

2 Centre for Human and Aerospace Physiological Sciences, King's College London, London, UK 3 Guy's & St Thomas’ NHS Foundation Trust and King's College London, National Institute of Health Research ...