TP53突变不仅深刻影响着慢性淋巴细胞白血病(CLL)的疾病进展轨迹,还直接关联到患者的不良预后,成为评估疾病严重程度与制定个性化治疗策略时不可忽视的重要因素。在备受瞩目的第29届欧洲血液协会年会(EHA ...
研究者使用冷冻电子显微镜、AlphaFold24和基于分子动力学的改进的综合方法,在大多数区域展示了亚纳米分辨率的apoB100的结构。该结构由一个大的球状N端结构域和一个约61纳米长的连续两亲β片组成,该β片像带一样包裹着LDL颗粒。准对称分布在β带两侧的是9个战略性的链间插入物,它们延伸到脂质表面,通过远程相互作用的网络提供额外的结构支持。
The media could not be loaded, either because the server or network failed or because the format is not supported.
Nike is in a slump. Sales are down, its stock has lost more than a quarter of its value over the past year and its new CEO needs some help turning around the aging athletic company. Enter Kim Kardashi ...
如果我们在事后反思时,发现自己当初的决定大多是出于情绪冲动(比如轻易放弃一份工作或婚姻等),并且现在能够用理性的思维认识到那是一个“错误”,那么就应该坦然接受自己过去的不足。但是如果当初你是出于明智做出的决定,那么,你就不要陷入现在的情绪冲动之中,轻 ...
Horst L?chel, professor of economics and co-chairman of the Sino-German Center at the Frankfurt School of Finance and Management shared his insights during the interview that China and Europe will ...
With boosting domestic consumption high on China's policy agenda for 2025, the country's consumer goods trade-in initiative is set to play a crucial role in driving economic growth and offsetting the ...
内华达州的奶牛群感染了此前从未在牛身上出现的H5N1禽流感病毒,这一消息披露后引起病毒学家和研究人员高度警惕。而且内华达州农业部发布的消息显示,想把该病毒从美国牛群中彻底清除,并不像联邦官员之前宣称或希望的那般容易。
一些您可能无法访问的结果已被隐去。
显示无法访问的结果