Human health is strongly intertwined with the health of the microbiome. A large number of studies have shown that the human ...

Both mTOR and c-Myc (unbolded) induce p53 activation when initially encountering DNA damage stress but are both capable of, upon overexpression or sustained activation (bolded), promoting ...

A recent study published in the Journal of Clinical Investigation by researchers at Johns Hopkins University School of Medicine and collaborators identified HMGA1 as a key epigenetic regulator that ...

These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...

Cancer Res (2025) 85 (4): 825.

"We have discovered a molecular switch that can revert the fate of cancer cells," said biologist Kwang-Hyun Cho.

Deleterious mutations in LKB1 are frequently observed in patients with epithelial ovarian cancer. However, its inconsistent effects on tumorigenesis and cancer progression suggest that its functional ...

Microplastics (MPs) are widely distributed environmental pollutants around the world. Although studies have demonstrated that MPs have adverse effects on human health, the relationship between MPs and ...

Clear cell sarcoma is deemed highly aggressive due to its early tendency to metastasize, genetic mutations, and difficulty in ...

Professor Kwang-Hyun Cho's research team of the Department of Bio and Brain Engineering at KAIST has captured the critical transition phenomenon at the moment when normal cells change into cancer ...

CIRBP Family, Tumors, Molecular Mechanisms, RNA-Binding Proteins, Cellular Stress Share and Cite: Cai, Y. , Wang, T. and Zhan ...