A research team from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences has revealed ...

As the global population ages, the importance of understanding neurological disorders increases exponentially. Two ...

James Desmet explores Targeted Protein Degradation, a potential drug discovery strategy capable of treating previously ...

Discover how targeting E3-X ligase could revolutionize SLE treatment by enhancing anti-inflammatory effects while reducing ...

Work at Foghorn Therapeutics Inc. has led to the design of proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase binding agent coupled to CREB-binding protein (CREBBP; CBP ...

News 2023; News 2022; News 2021; News 2020; News 2019; News 2018; News 2017; 2024 graduation ceremony and Biology Section awards. The award ceremony to ...

在大脑的神秘世界中，神经干细胞（Neural Stem Cells, NSC）的静息和增殖之间的微妙平衡至关重要。这种平衡不仅影响成人神经发生和体内平衡，还决定了大脑能否有效地修复和再生。小的泛素相关修饰物（SUMO, Small Ubiquitin ...

Aurigene Oncology Ltd. has described proteolysis targeting chimeras (PROTACs) comprising an E3 ubiquitin ligase binding moiety coupled to a probable global transcription activator SNF2L2 (SMARCA2; ...

Molecular Cancer Research publishes articles featuring novel, basic cancer research discoveries that prioritize broad molecular and cellular processes. Areas of emphasis include cell cycle and ...