HEFEI, China I February 25, 2025 I Kangpu Biopharmaceuticals, Ltd. ("Kangpu") today announced that the Company has received IND approval from the CDE (Center ...

Researchers identify associations between B12 levels currently accepted as normal and markers of neurological injury or ...

A new review published in Genes & Diseases explores the pivotal role of the ubiquitin-proteasome system (UPS) in regulating the tumor microenvironment (TME) and driving cancer progression. The study ...

E1s and E2s first work generically across the cell to activate and prepare ubiquitin for attachment. E3 ligases then ensure that the tag is added to the right protein; as such, hundreds of specific ...

Johns Hopkins University School of Medicine researchers have discovered a dual regulatory mechanism safeguarding ...

A growing body of research suggests that infections, including those caused by common bacteria in gum disease, could ...

Recent research links Alzheimer's disease to bacterial gum infections, specifically the pathogen Porphyromonas gingivalis.

Ubiquitin-specific protease 7 (USP7) is involved in DNA repair and cell cycle progression and, due to its control over the ubiquitination of key proteins, may impact oncogenes like MDM2 and c-Myc, as ...

Beijing Earthwise Technology Co. Ltd. has synthesized E3 ubiquitin-protein ligase CBL-B inhibitors reported to be useful for the treatment of cancer.

One of the first things that students learn when they enter a biology class is the central dogma: DNA → RNA → ...

In recent years, a growing number of scientific studies have backed an alarming hypothesis: Alzheimer's disease isn't just a disease, it's an infection. While the exact mechanisms of this infection ...