胰腺癌( PC)是一种侵袭性肿瘤,在过去十年中,5年总生存率( OS)基本保持不变,仅为12%。预计到2040年,PC将成为美国癌症相关死亡的第二大原因。尽管诊断时的中位年龄为71岁,但早发性胰腺癌( EOPC)( ...
在转移性疾病中,接受靶向治疗的EOPC患者生存率明显高于未接受靶向治疗者,显示出基因变异可能是治疗效果的关键。因此,医生应高度重视对所有胰腺癌患者,尤其是年轻患者,进行基因检测,以实现个性化治疗和更佳的保健结局。
Barcelona-based scientific leader brings insights and experience in translational oncology research and clinical development CAM ...
Published in Cell Reports Medicine, results of a VHIO-led study support the feasibility of using RAD51 testing to complement next-generation sequencing (NGS) for precise patient stratification and ...
co-leader of VHIO's Prostate Cancer Group, and co-corresponding author of this study. "However, several challenges of NGS testing still impede the widespread implementation of precision medicine ...
The incidence of advanced prostate cancer in California rose markedly in the decade since doctors stopped routinely screening all men for the disease, according to a new study by UC San Francisco ...
Risk factors for relapse based on the molecular profiling of Japanese patients with stage II colorectal cancer.
Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...
Randomized Comparison of Magnetic Resonance Imaging Versus Transurethral Resection for Staging New Bladder Cancers: Results From the Prospective BladderPath Trial Over the past 15 years, the landscape ...
MYC is a pleiotropic transcription factor involved in multiple cellular processes. While its mechanism of action and targets are not completely elucidated, it has a fundamental role in cellular ...