A state of the art Inveon Dedicated PET scanner from Siemens with a high-resolution of 1.4 mm is available for small animal studies. It can do whole body imaging of rodents, rabbits and other small animals. The facility is equipped to carry out detailed in vivo and ex vivo studies of various biomarkers. Some examples are shown below:

2012年9月1日 · Small-animal PET refers to imaging of animals such as rats and mice using a small, high-resolution PET scanner designed specifically for this purpose. Compared with a human PET scanner, a small-animal PET scanner is used for subjects that typically are 2 to 3 orders less in weight and volume than a human.

2019年9月13日 · To evaluate the mouse hotel under standard in vivo imaging conditions, 4 mice were simultaneously scanned by dynamic 18 F-FDG PET/CT over 60 min, and quantified images were compared with those acquired using a single mouse bed.

2024年8月15日 · β-amyloid (Aβ) small animal PET facilitates quantification of fibrillar amyloidosis in Alzheimer's disease (AD) mouse models. Thus, the methodology is receiving growing interest as a monitoring tool in preclinical drug trials.

2023年6月1日 · Here, we report an ultrahigh-resolution small-animal PET scanner we developed that can provide a resolution approaching 0.6 mm to visualize mouse brain function with unprecedented detail. Methods: The ultrahigh-resolution small-animal PET scanner has an inner diameter of 52.5 mm and axial coverage of 51.5 mm.

To evaluate the mouse hotel under standard in vivo imaging conditions, 4 mice were simultaneously scanned by dynamic 18 F-FDG PET/CT over 60 min, and quantified images were compared with those acquired using a single mouse bed.

2022年9月22日 · Automatic analysis toolboxes are popular in brain image analysis, both in clinical and in preclinical practices. In this regard, we proposed a new toolbox for mouse PET–CT brain image analysis...

2019年2月11日 · Here we set out to evaluate the feasibility of using small-animal PET employing [11 C]DASB ( [11 C]-3-amino-4- (2-dimethylaminomethyl-phenylsulfanyl)-benzonitrile) as a radiotracer to measure...

2020年3月24日 · We propose a generic method for quantification of TSPO PET scans in the mouse by taking the focus away from finding an appropriate reference or pseudo-reference region and using a data-driven approach instead, to extract a blood input function from the whole-body image of the mouse.

2021年12月4日 · Using PET/CT studies in Hualpha-Syn (A53T) α-synuclein mutant mice, we recently reported [18 F]FDG brain deficits, limb muscle deficits and reduction of metabolic activity in regions of the spinal cord [23].