Immunogenicity is the ability of a foreign substance, such as an antigen, to provoke an immune response in the body of a human or other animal. It may be wanted or unwanted:

The meaning of IMMUNOGENIC is relating to or producing an immune response. How to use immunogenic in a sentence.

2023年7月4日 · The main difference between antigenicity and immunogenicity is that antigenicity is the ability of a particular substance to be recognized by antibodies produced as a result of a specific immune response. In contrast, immunogenicity is the ability of a substance to induce an immune response that is either cellular or humoral.

Immunogenicity is the capacity to provoke an immune response. When one refers to an immunogenic molecule, this means that the molecule is capable of triggering an immune response by itself, not when conjugated to another macromolecule.

The immune system recognizes antigens on the surface of substances it sees as foreign, such as vaccines, bacteria, viruses, or cancer cells, and makes an immune response against them. The strength of an immune response depends on how immunogenic a substance is.

The best proactive approach to immunogenicity mitigation is to develop more predictive tools and, where possible, design out immunogenic sequences early in drug development.

2020年1月1日 · Immunogenicity is a term generally associated with an immune response. In the case of a biotherapeutic drug, immunogenicity can impact the safety, efficacy, and pharmacokinetic profile of a drug, ultimately leading to unwanted side effects.

Immunogenicity is the ability of a vaccine to elicit immune responses, which can be measured in many ways [28]. Immunogenicity has been assessed in patients with hematologic malignancies by seroconversion, presence of neutralizing antibodies, and T-cell responses to SARS-CoV-2.

2 天之前 · Our research shows that cryptic peptides are the primary class of tumor antigens in OC. These peptides are immunogenic and may play a role in the observed clinical immune responses against OC. Overall, they represent a promising source of antigens for the potential future development of targeted immunotherapies.

The concept of the immunogenicity of an antigen is frequently encountered in the context of vaccine development, an area of intense interest currently due to the emergence or re-emergence of infectious pathogens with the potential for worldwide spread.