Bacterial artificial chromosome - Wikipedia
A bacterial artificial chromosome (BAC) is a DNA construct, based on a functional fertility plasmid (or F-plasmid), used for transforming and cloning in bacteria, usually E. coli. [1][2][3] F-plasmids play a crucial role because they contain partition genes that promote the even distribution of plasmids after bacterial cell division.
Bacterial Artificial Chromosome (BAC) - National Human …
1 天前 · A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). BACs are often used in connection with DNA sequencing. Segments of an organism's DNA, ranging from 100,000 to about 300,000 base pairs, can be inserted into BACs. The BACs, with their inserted DNA, are ...
细菌人工染色体 - 百度百科
细菌人工染色体（Bacterial artificial chromosome，BAC）是指一种以F质粒（F-plasmid）为基础建构而成的细菌染色体克隆载体，常用来克隆150kb左右大小的DNA片段，最多可保存300kb个碱基对。
細菌人工染色體 - 维基百科，自由的百科全书
細菌人工染色體 （Bacterial artificial chromosome， BAC）是指一種以 F質體 （F-plasmid）為基礎建構而成的 載體，最多可保存300000個 鹼基對 （平均約150000）。
Application of a Bacterial Artificial Chromosome Modification …
Bacterial artificial chromosomes (BACs) are optimal for harboring long fragments of genomic DNA or large cDNA up to 300 kb in size. Therefore, BACs are available to produce transgenic cells and animals for the functional studies of genes. However, BAC can insert DNA randomly into the host genome, possibly causing unpredicted expression.
Bacterial Artificial Chromosome - an overview - ScienceDirect
Bacterial artificial chromosomes (BACs) are large genomic clones that are stably maintained in Escherichia coli. Because they are frequently large enough to contain an entire gene and its associated regulatory elements, BACs can serve as a source of …
Construction and screening of BAC libraries made from ... - Nature
2007年6月28日 · Bacterial artificial chromosome (BAC) libraries are the large DNA insert libraries of choice and valuable tools for the map-based cloning of target quantitative trait loci, physical...
Bacterial Artificial Chromosome - an overview - ScienceDirect
The bacterial artificial chromosome (BAC) system is useful for creating a representation of the genomes of target species. The system is advantageous in that it can accommodate exogenous inserts that are very large (>100 kilobases, kb), thereby allowing entire eukaryotic genes (including flanking regulatory regions) to be encompassed in a ...
Bacterial Artificial Chromosome - an overview - ScienceDirect
Bacterial artificial chromosomes (BACs) are large genomic clones that are stably maintained in Escherichia coli. Because they are frequently large enough to contain an entire gene and its associated regulatory elements, BACs can serve as a source of …
Bacterial Artificial Chromosomes | SpringerLink
Bacterial Artificial Chromosomes, Second Edition expands upon the previous edition with current, detailed methods developed for working with BACs. Updated chapters included in this edition present fundamental techniques used for BAC construction and characterization, advanced procedures for introducing modifications, achieving gene expression ...
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