Connexin | Hyperfast Fibre Broadband Deals in Hull | November …
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Music, Comedy & More - What's On | Connexin Live Hull
2024年12月13日 · What's on at Connexin Live Hull? Along with headline bands, music & movies, Connexin Live, Hull hosts snooker, sport & comedy stars. View our events schedule here!
Connexins: Mechanisms regulating protein levels and intercellular ...
Gap junction channels are comprised of integral multi-pass transmembrane proteins called connexins [1, 2]. Connexins have four transmembrane domains that are linked by one intracellular loop, two extracellular loops, and have N- and C-terminal cytoplasmic domains.
Connexins: a myriad of functions extending beyond assembly of …
2009年3月12日 · This review provides an updated overview of current knowledge of connexins and their interacting proteins, and it describes connexin modulation in disease and tumorigenesis.
Gap junction protein Connexin-43 is a direct transcriptional …
2018年9月21日 · Connexins are the primary components of gap junctions, providing direct links between cells under many physiological processes. Here, we demonstrate that in addition to this canonical role,...
Connexins in cancer: bridging the gap to the clinic | Oncogene
2019年2月27日 · Targeting connexin 43 with alpha-connexin carboxyl-terminal (ACT1) peptide enhances the activity of the targeted inhibitors, tamoxifen and lapatinib, in breast cancer: clinical implication...
Therapeutic strategies targeting connexins - Nature
2018年10月12日 · Here, we review the roles of connexins in health and disease, focusing on the potential of connexins as therapeutic targets in acquired and inherited diseases as well as wound repair, while...
Connexins and the Epithelial Tissue Barrier: A Focus on Connexin 26
Connexins (CXs) are the structural building blocks of gap junctions, four-transmembrane domain spanning proteins with intracellular N- and C-tails (Figure 1). In humans, connexins are encoded by a multigene family containing twenty-one members classified by their molecular weight ranging from 23 to 62 kDa in size (CX23-CX62) [6].
Connexins: A Guide - SpringerLink
Connexins: A Guide is a practical and valuable reference and text covering a wide scope of information about the connexin family of membrane channel proteins.
Connexins and Disease - PMC - National Center for Biotechnology …
In the present work, we review current knowledge on the role of connexins in diseases associated with the heart, nervous system, cochlea, and skin, as well as cancer and pleiotropic syndromes such as oculodentodigital dysplasia (ODDD).
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