The most common form of a microtubule consists of 13 protofilaments in the tubular arrangement. Microtubules are one of the cytoskeletal filament systems in eukaryotic cells. The microtubule cytoskeleton is involved in the transport of material within cells, carried out by motor proteins that move on the surface of the microtubule.

微管（microtubule，MT）是由微管蛋白和微管结合蛋白组成的中空圆柱状结构。 在不同的细胞中微管具有相似的结构特性，对低温、高压和秋水仙素等药物敏感。

微管（英語： microtubule ）是细胞骨架的一个组成部分，遍布於细胞质中。微管蛋白的这些管状聚合物可以增长长达50微米，具有25微米的平均长度， [1] 并且是高度动态的。微管的外径约为24纳米，而内直径为约12纳米。

2017年4月28日 · Microtubule Definition. Microtubules are microscopic hollow tubes made of the proteins alpha and beta tubulin that are part of a cell’s cytoskeleton, a network of protein filaments that extends throughout the cell, gives the cell shape, and keeps its organelles in place.

Whether a microtubule grows or shrinks is determined by the rate of tubulin addition relative to the rate of GTP hydrolysis. As long as new GTP-bound tubulin molecules are added more rapidly than GTP is hydrolyzed, the microtubule retains a GTP cap …

2025年2月12日 · Microtubule, tubular structure of indefinite length, constructed from globular proteins called tubulins, which are found only in eukaryotic cells. Microtubules have several functions. For example, they provide the rigid, organized components of the cytoskeleton that give shape to many cells, and

In the lens, as well as other systems, distinct roles for characteristically dynamic microtubules and stabilized populations are coming to light. Understanding the mechanisms of microtubule stabilization and the associated microtubule post-translational …

2023年2月17日 · In a microtubule, the subunits are organized such that they all face the same direction to form 13 parallel protofilaments. Thus, the microtubule is polar with the alpha-tubulin exposed at one end and beta-tubulin at the other.

A single microtubule contains 10 to 15 protofilaments (13 in mammalian cells) that wind together to form a 24 nm wide hollow cylinder.

2024年10月1日 · The continued delivery of materials into synaptic compartments is essential to replenish components, which also depends on microtubule-based trafficking. How microtubule dynamics controls synaptic structure and function is largely unexplored, but recent studies point to a role of tubulin PTMs.