Atherothrombosis: A widespread disease with unpredictable and …
2004年7月1日 · Atherothrombosis, characterised by atherosclerotic lesion disruption with superimposed thrombus formation, is the major cause of acute coronary syndromes (ACS) and cardiovascular death. It is the leading cause of mortality in the industrialised world.
Atherothrombosis: Disease Initiation, Progression, and Treatment ...
Atherothrombosis describes a disease process that begins with atherosclerosis and predisposes to thrombosis in the artery. In the 1850s, Virchow 1 described atherosclerosis as an inflammatory and prothrombotic process.
Atherothrombosis | Circulation - AHA/ASA Journals
2015年10月14日 · Illustration of potential mechanisms of diet-induced RBC dysfunction and atherothrombosis. Thrombosis-, inflammation-, and blood flow–dependent mechanisms of RBC dysfunction influencing atherosclerosis, ischemia, and thrombotic complications.
Pathophysiology of atherothrombosis: Mechanisms of thrombus …
Atherothrombotic events such as myocardial infarction and ischemic stroke are major causes of morbidity and mortality worldwide. Atherosclerotic plaque disruption and subsequent thrombus formation are considered to be critical processes involved in the onset of atherothrombotic events.
Pathophysiology of atherothrombosis: Mechanisms of thrombus …
The underlying mechanisms of atherothrombosis comprise plaque disruption and subsequent thrombus formation. Arterial thrombi are thought to mainly comprise aggregated platelets as a result of high blood velocity.
Atherothrombosis: Epidemiology, Pathophysiology, and …
2004年3月1日 · Atherothrombosis, defined as atherosclerosis with superimposed thrombus formation, is a generalized and diffuse progressive process that affects multiple vascular beds.
Antithrombotic Therapy: Prevention and Treatment of …
2020年8月11日 · Traditionally, platelets were regarded key players in atherothrombosis; hence much focus has been put on antiplatelet agents, initially mostly aspirin. Given the efficacy/safety profile, primary prevention with aspirin has been extensively studied.
Atherothrombosis: a major health burden - PubMed
Atherothrombosis is a leading cause of mortality, and stroke is the leading cause of disability in adults, the second most important cause of dementia and the third most common cause of death in Western countries. Ischaemic stroke accounts for 80% of strokes and atherothrombosis accounts for approximately 20% of all strokes. Criteria for ...
The Year in Atherothrombosis | Journal of the American College …
2011年8月1日 · Highlights of the Year in Atherothrombosis. The benefits of reduced smoking, hypertension, and dyslipidemia over the past decades have been partially offset by obesity (2,3,5). Carotid plaque neovascularization and intraplaque hemorrhage were associated with subsequent cardiovascular events (21).
Arterial Thrombosis: Present and Future | Circulation - AHA/ASA …
2024年9月16日 · Most arterial thrombi form on top of disrupted atherosclerotic plaques, a process known as atherothrombosis. Although concomitant activation of platelets and coagulation is a hallmark of atherothrombosis, antiplatelet therapy remains the cornerstone of ACS treatment.