The Role of Different Subsets of Regulatory T Cells in ...
2012年10月24日 · It is now known that various subsets of Tregs exist in immune system including nTregs, CD8 + Treg, Tr1 regulatory cells, Th3 cells, and natural killer like T (NKT) cells.
Regulatory T cells in cancer immunosuppression - Nature
2019年1月31日 · Regulatory T (Treg) cells are implicated in cancer immune evasion and escape and thus contribute to tumour development and progression.
Optimizing human Treg immunotherapy by Treg subset selection …
2018年1月11日 · By studying the gene expression profiles in over 40 reported Treg subset divisions, a recent study concluded that human naïve Tregs and DR+ memory Tregs truly represented distinct subsets...
Intratumoral regulatory T cells: markers, subsets and their ... - PubMed
In this review, we discuss markers that serve to identify certain Treg cell subsets, distinguished by chemokine receptors, IRs and cytokines that facilitate their migration, stability and function in the TME.
The role of Treg cell subsets in allergic disease - PubMed
In this review, we discuss the six subsets of Tregs, natural (nTregs), inducible Treg (iTregs), inducible costimulatory (ICOS+ Tregs), Tr1, CD8+ Tregs and IL-17-producing Tregs, and their role in allergic disease and allergen immune tolerance.
Identification and classification of distinct surface markers of T ...
To screen Treg and Tconv cells, peripheral blood mononuclear cells (PBMCs) were isolated from volunteers, stained with a commercially available lyophilized antibody array comprising 371 surface antigens, and analyzed by flow cytometry.
How do Regulatory T Cells Work? - PMC - PubMed Central (PMC)
Abstract. CD4 + T cells are commonly divided into regulatory T (Treg) cells and conventional T helper (Th) cells. Th cells control adaptive immunity against pathogens and cancer by activating other effector immune cells. Treg cells are defined as CD4 + T cells in charge of suppressing potentially deleterious activities of Th cells. This review briefly …
Subsets of regulatory T cells and their roles in allergy
2014年5月12日 · The suppressive actions of Tregs on other immune cells such as effector T cells, B cells, eosinophils and mast cells may help to explain the reasons why Tregs are capable of controlling acquired immunity.
Functionally distinct subsets of human FOXP3+ Treg cells that ...
2012年5月5日 · Based on expression of the chemokine receptors CCR6, CXCR3, CCR4, and CCR10, we identified 4 separable populations of FOXP3 + Treg cells in human peripheral blood that mirror different Th cell subsets phenotypically.
Functionally distinct subsets of human FOXP3+ Treg cells that
2012年5月10日 · Based on chemokine receptor expression, we identified distinct populations of Treg cells in human blood expected to colocalize with different Th cell subsets.
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