5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. [ 1 ] [ 2 ] [ 3 ] They mediate both excitatory and inhibitory neurotransmission .

Serotonin, also known as 5-hydroxytryptamine (5-HT), is a monoamine neurotransmitter. It also acts as a hormone.

There are currently 14 known serotonin receptors, including the serotonin 5-HT 1 (1A, 1B, 1D, 1E, 1F), 5-HT 2 (2A, 2B, 2C), 5-HT 3, 5-HT 4, 5-HT 5 (5A, 5B), 5-HT 6, and 5-HT 7 receptors.

Learn more about 5-HTP uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain 5-HTP.

2023年7月30日 · Serotonin, or 5-hydroxytryptamine (5-HT), is a neurotransmitter with an integral physiological role in the human body; it regulates various activities, including behavior, mood, memory, and gastrointestinal homeostasis.

2023年3月1日 · 5-HTP is a compound that is believed to help increase levels of serotonin in your body. This may be beneficial for several conditions, including depression, insomnia, migraines, and more.

The neurotransmitter 5-Hydroxytryptamine (5-HT), or serotonin, is most commonly known for its role in the pathophysiology of various neuropsychiatric disorders. However, an abundance of literature based on serotonergic manipulation in animal models has yielded knowledge of the plethora of physiological process directly and indirectly influenced ...

5-HT receptors are metabotropic receptors found in the brain, with subtypes like 5-HT 5A and 5-HT 5B. In humans, the HTR5A gene encodes for a functional protein, mainly located in regions such as the cerebral cortex and hippocampus.

Serotonin (5-HT) neurotransmission is intimately linked to anxiety and depression and a diverse body of evidence supports the involvement of the main inhibitory serotonergic receptor, the serotonin-1A (5-HT1A) subtype, in both disorders. In this ...

This review addresses the roles that both different gene polymorphisms involved in 5-HT signaling and the different 5-HT receptors (i.e. 5-HT 1A, 5-HT 1B, 5-HT 4, and 5-HT 7) may have in the pathophysiology of depression and the antidepressant response. A streamlined knowledge of these 5-HT signaling-related polymorphisms and receptors may ...