Adeno-associated virus - Wikipedia
Adeno-associated viruses (AAV) are small viruses that infect humans and some other primate species. They belong to the genus Dependoparvovirus, which in turn belongs to the family Parvoviridae.
Adeno-Associated Virus (AAV) as a Vector for Gene Therapy
2017年7月1日 · Adeno-associated virus (AAV) is a versatile viral vector technology that can be engineered for very specific functionality in gene therapy applications. To date, AAV has been shown to be safe and effective in preclinical and clinical settings.
Adeno-associated Virus (AAV) Guide - Addgene
Learn about the types of plasmids used to produce AAV in the lab. Addgene’s AAV Guide will teach you about AAV components, serotypes, pseudotyping, and more.
Adeno-associated virus as a delivery vector for gene therapy
2024年4月3日 · Adeno-associated virus (AAV) has emerged as a pivotal delivery tool in clinical gene therapy owing to its minimal pathogenicity and ability to establish long-term gene expression in different...
Adeno-associated Virus (AAV) Plasmids - Addgene
Adeno-associated viruses (AAV) are small viruses originally discovered as contaminants of adenovirus stocks. One major advantage of using AAV for research is that it is replication-limited and typically not known to cause disease in humans.
Adeno-associated virus vector as a platform for gene therapy …
2019年2月1日 · Adeno-associated virus (AAV) vectors are the leading platform for gene delivery for the treatment of a variety of human diseases. Recent advances in developing clinically desirable...
Production of adeno-associated virus vectors for in vitro and in …
2019年9月19日 · Among viral delivery systems, adeno-associated viruses (AAVs) are relatively safe and demonstrate high gene transfer efficiency, low immunogenicity, stable long-term expression, and...
Adeno-associated virus vector as a platform for gene therapy …
Adeno-associated virus (AAV) is recognized by glycosylated cell surface receptors of the host. This triggers internalization of the virus via clathrin-mediated endocytosis. AAV then traffics through the cytosol mediated by the cytoskeletal network.
Adeno-associated Virus (AAV): Structure, Vector, Gene Therapy, …
What is an adeno-associated virus? Adeno-associated virus (AAV) was organically discovered in 1965 as a contaminant in adenovirus cultures. It belongs to the genus Dependovirus of the Parvovirus family.
Adeno-associated virus vector as a platform for gene therapy ... - PubMed
Adeno-associated virus (AAV) vectors are the leading platform for gene delivery for the treatment of a variety of human diseases. Recent advances in developing clinically desirable AAV capsids, optimizing genome designs and harnessing revolutionary biotechnologies have contributed substantially to t ….
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