Amlodipine: Uses, Interactions, Mechanism of Action
Amlodipine is commonly used in the treatment of high blood pressure and angina. Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), an important vasodilator that decreases blood pressure 3. The option for single daily dosing of amlodipine is an attractive feature of this drug Label. Type
Amlodipine - StatPearls - NCBI Bookshelf
2024年4月21日 · Amlodipine, an oral dihydropyridine calcium channel blocker, demonstrates prolonged efficacy by inhibiting voltage-dependent L-type calcium channels. This action interrupts initial calcium influx, distinguishing it within its pharmacological class.
Amlodipine - Wikipedia
Amlodipine, sold under the brand name Norvasc among others, is a calcium channel blocker medication used to treat high blood pressure, coronary artery disease (CAD) [10] and variant angina (also called Prinzmetal angina or coronary artery vasospasm, among other names). [11] It is taken orally (swallowed by mouth). [10]
AmLODIPine: Dosage, Mechanism/Onset of Action, Half-Life
2020年2月9日 · Includes AmLODIPine indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more.
Calcium Channel Blockers - StatPearls - NCBI Bookshelf
2024年2月22日 · Reports suggest that methylene blue, particularly in amlodipine overdose patients, may be effective in managing vasodilatory shock. Phosphodiesterase inhibitors represent another option in CCB therapy; they increase cardiac output …
Calcium Channel Blockers - PMC
Calcium channel blockers, which dilate arteries by reducing calcium flux into cells, effectively lower blood pressure, especially in combination with other drugs, and some formulations of agents of this class are approved for treating angina or cardiac dysrhythmias.
Amlodipine: Package Insert / Prescribing Info - Drugs.com
Amlodipine besylate tablets, USP are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.
Amlodipine: MOA, Uses, Dosage, Side Effects - Medcrine
2020年8月4日 · Amlodipine is a dihydropyridine calcium-channel blocker. It is a peripheral and coronary vasodilator, but, unlike the calcium-channel blockers verapamil or diltiazem, has little or no cardiac conduction and negative inotropic activity is rarely seen at therapeutic doses.
Calcium channel blockers in the management of chronic ... - UpToDate
2023年6月15日 · Calcium channel blockers are a heterogeneous group of compounds used in a variety of cardiovascular disorders such as stable angina pectoris, vasospastic angina, hypertension, hypertrophic cardiomyopathy, and supraventricular arrhythmias.
Amlodipine is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Experimental data suggest that amlodipine binds to both dihydropyridine and nondihydropyridine binding sites.
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