Brefeldin A - Wikipedia
Brefeldin A is a lactone antiviral produced by the fungus Penicillium brefeldianum. [1] Brefeldin A inhibits protein transport from the endoplasmic reticulum to the golgi complex indirectly by preventing association of COP-I coat [2] to the Golgi membrane.
Brefeldin A (BFA，布雷非德菌素 A) - 仅供科研 | 蛋白质转运抑制 …
2017年9月6日 · Brefeldin A (BFA) 是一种内酯抗生素，是蛋白质运输的特定抑制剂。 Brefeldin A 阻断分泌蛋白和膜蛋白从内质网向高尔基体的转运。 Brefeldin A 也是一种自噬 (autophagy) 和 mitophagy 抑制剂。
布雷非德菌素A - 维基百科，自由的百科全书
布雷非德菌素A（英語： Brefeldin A ）是一种大环内酯类抗生素，由布雷正青霉菌（Penicillium brefeldianum）等真菌组织产生 [1] 。 布雷非德菌素A能通过阻止 COPI 被膜小泡的形成来抑制从 内质网 到 高尔基体 的蛋白质转运 [ 2 ] 。
蛋白转运抑制剂--Brefeldin A布雷非德菌素A - 翌圣生物
Brefeldin A布雷非德菌素A，简称BFA，是一种从真菌中分离的内酯抗生素，是蛋白质运输的特定抑制剂。 BFA可抑制coat proteins（如β-COP and ADP-ribosylation factor (ARF)）与高尔基体的结合并抑制GDP-GTP交换，破坏高尔基体的结构并抑制其功能，进而特异地阻断蛋白质从内质网 ...
Brefeldin A - Cell Press
1999年4月16日 · Brefeldin A is a small hydrophobic compound produced by toxic fungi that has dramatic effects on mammalian cells. Within minutes of brefeldin A treatment the Golgi complex disassembles and redistributes into the endoplasmic reticulum (ER): this makes it a potent inhibitor of secretion, and a very useful tool for cell biologists.
Brefeldin A | ER-Golgi protein trafficking inhibitor - InvivoGen
Brefeldin A (BFA) is a potent and reversible inhibitor of vesicle formation and protein trafficking between the endoplasmic reticulum (ER) and the Golgi apparatus. BFA is commonly utilized as an inhibitor of protein secretion in cellular assays.
eBioscience™ Brefeldin A 溶液 (1000X) - 赛默飞世尔科技公司
Brefeldin A 是一种细胞内蛋白转运抑制剂。孵育细胞时在培养物中添加 Brefeldin A 可阻断蛋白向高尔基体复合体 (GC) 的转运并使蛋白在内质网 (ER) 中蓄积。在细胞体外活化的最后几小时内添加 Brefeldin A 素可增强细胞内细胞因子的检测。
Brefeldin A's effects on endosomes, lysosomes, and the TGN …
1991年11月1日 · Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum
Brefeldin A - an overview | ScienceDirect Topics
Brefeldin A (BFA) is a drug that specifically blocks classical vesicle-mediated trafficking by interfering with the Plasmodium ADP ribosylation factor GDP–GTP exchange protein [a key molecule required for the assembly of coat protein (COP), …
brefeldin A | C16H24O4 | CID 5287620 - PubChem
Brefeldin A is a metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity. It has a role as a Penicillium metabolite.
- 某些结果已被删除