Bufotoxin - Wikipedia
Bufotoxins are a family of toxic steroid lactones or substituted tryptamines of which some are toxic. They occur in the parotoid glands, skin, and poison of many toads (Bufonidae family) and other amphibians, and in some plants and mushrooms. [1][2][3] The exact composition varies greatly with the specific source of the toxin.
Bufotoxin - an overview | ScienceDirect Topics
The bufotoxins are cardiac glycosides. They bind to and inhibit sodium-potassium ATPase in a manner similar to other cardiac glycosides, such as digoxin and digitoxin. The inhibition of the sodium-potassium ATPase results in an increased extracellular concentration of potassium and an increased intracellular concentration of sodium.
蟾酥 - 维基百科，自由的百科全书
蟾酥 （拉丁語： venenum bufonis，英語： toad venom） [1] 主成分为 蟾毒素 （bufotoxin），是 中药材 攻毒杀虫止痒药的一种，该药材出自于《药性论》一书，有解毒止痛的功效。 蟾酥为 蟾蜍科 动物 中华大蟾蜍 （Bufo gargarizans Cantor）或 黑眶蟾蜍 （Duttaphrynus melanostictus Schneider）的 耳后腺 和 皮肤腺体 的干燥分泌物 [2]，蟾酥的药性辛、温，有小毒；入 心经 [3]。 蟾酥主要产于 吉林 、 山东 、 辽宁 、 江苏 等地，主要采收于夏秋两季。 一般采收将捕获的 …
Bufotoxin | Poisonous, Amphibians, Toads | Britannica
Bufotoxin, a moderately potent poison secreted in the skin of many anuran amphibians, especially the typical toads (genus Bufo). The milky fluid contains several identifiable components: bufagin, with effects on the heart similar to those of digitalis; bufotenine, a hallucinogen; and serotonin, a
Toads phenotypically adjust their chemical defences to …
2019年2月28日 · We found that, compared to toads captured from natural habitats, adults from both types of anthropogenic habitats had larger toxin glands (parotoids) and their toxin secretion contained higher...
Bufotoxin | C40H60N4O10 | CID 20054854 - PubChem
Bufotoxin | C40H60N4O10 | CID 20054854 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Bufotoxin | The Merck Index Online
Bufotoxin UNII L30U3VAH5C Molecular formula C 40 H 60 N 4 O 10 Molecular weight 756.94 Percent composition C 63.47%, H 7.99%, N 7.40%, O 21.14% Standard InChI
Bufotoxin - 药物在线
Properties: Monohydrate, bitter needles from alc, dec 205°. uv max: 295 nm (log e 3.74). Freely sol in methanol, pyridine, sparingly sol in abs alc. Practically insol in water, ether, acetone, chloroform, petr ether.
Chemical profiling and cytotoxicity assay of bufadienolides in toad ...
2016年7月1日 · Eight bufotoxins were identified in toad skin responsible for the cytotoxicity for the first time. Our research provides valuable chemical evidence for the appropriate processing method, quality control and rational exploration of toad skin and toad venom for the development of anticancer medicines. 1. Introduction.
Toad venom bufadienolides and bufotoxins: An updated review
2023年5月8日 · In this work, we reviewed data related to anticancer activity of bufadienolides such as bufalin, arenobufagin, bufotalin, gamabufotalin, cinobufotalin, and cinobufagin and their derivatives....