Cannabidiol - Wikipedia
Cannabidiol (CBD) is a phytocannabinoid, one of 113 identified cannabinoids in cannabis plants, along with tetrahydrocannabinol (THC), and accounts for up to 40% of the plant's extract. [17] Medically, it is an anticonvulsant used to treat multiple forms of epilepsy. [4]
Cannabidiol | C21H30O2 | CID 644019 - PubChem
Cannabidiol, or CBD, is one of at least 85 active cannabinoids identified within the Cannabis plant. It is a major phytocannabinoid, accounting for up to 40% of the Cannabis plant's extract, that binds to a wide variety of physiological targets of the endocannabinoid system within the body.
The Essential Medicinal Chemistry of Cannabidiol (CBD) - PMC
CBD is Just One Molecule in the Vast Chemical Space of Cannabinoids. Formally, CBD can be considered to have a tetrahydro-biphenyl skeleton: a bicyclic core that represents an adduct formed by the monoterpene, p-cymene, and the alkylresorcinol derivative olivetol .
Cannabidiol - American Chemical Society
2017年2月6日 · Cannabidiol (CBD) is the term for a family of cannabinoids that are isomers of THC, the chief psychoactive component of marijuana. These compounds are not psychoactive, but they are useful for controlling pain and other medical conditions.
Antioxidative and Anti-Inflammatory Properties of Cannabidiol
It has been shown that CBD by activating A 2A adenosine receptors can reduce the level of vascular cell adhesion molecule (VCAM-1) in endothelial cells in SJL/J mice, which may provide a new mechanism to control neuroinflammatory diseases such as multiple sclerosis (MS) .
Overview of cannabidiol (CBD) and its analogues: Structures, …
2020年4月15日 · CBD has potent anti-proliferation properties in several tumour cell lines and can be used as a small-molecule chemotherapeutic. Although some molecular signalling pathways and related targets of CBD have been revealed and summarized in the present review, unresolved issues remain.
Molecular and Cellular Mechanisms of Action of Cannabidiol - MDPI
2023年8月9日 · The molecular targets where CBD exerts its direct effects are TRPV1, 5-HT1A, PPARγ, and L-type Ca 2+ channels, which are responsible for its anxiolytic effects, blocking the transduction of chronic pain by affecting sensory nociceptors, modifying intracellular concentrations of calcium and the resting potential of excitatory cells, and ...
The Essential Medicinal Chemistry of Cannabidiol (CBD)
2020年8月17日 · Herein, we offer a critical review of the published medicinal chemistry properties of CBD, as well as precise definitions of CBD-containing substances and products, distilled to reveal the essential factors that impact its development as a …
The Cannabidiol -CBD- Molecule from Cannabis - World of Molecules
Cannabidiol (CBD) is a naturally occurring cannabinoid component of cannabis. It is one of at least 113 cannabinoids identified in hemp plants. While delta-9-tetrahydrocannabinol (THC) is the major active ingredient, cannabidiol (CBD) can make up about 40% of cannabis extracts depending on the plant.
An overview on synthetic and biological activities of cannabidiol (CBD …
2023年11月1日 · Among them, the most abundant and widely studied compounds are cannabidiol (CBD) and Δ 9 -tetrahydrocannabinol (Δ 9 -THC) (Fig. 1). Δ 9 -THC is the ingredient with the highest content in cannabis [2], and is also the main constituent in the psychoactive effect of cannabis, through the CB 1 receptor [3].