What is CRISPR? A bioengineer explains | Stanford Report
2024年6月10日 · Here, Stanford University bioengineer Stanley Qi explains how CRISPR works, why it’s such an important tool, and how it could be used in the future – including current …
CRISPR technology: A decade of genome editing is only the …
This Review covers the origins and successes of CRISPR-based genome editing and discusses the most pressing challenges, which include improving editing accuracy and precision, …
Genome editing with CRISPR–Cas nucleases, base editors ... - Nature
2020年6月22日 · Four classes of CRISPR-based genome editing agents are nucleases, base editors, transposases/recombinases and prime editors. Examples of starting substrates and …
What is CRISPR/Cas9? - PMC - PubMed Central (PMC)
CRISPR/Cas9 is a gene-editing technology which involves two essential components: a guide RNA to match a desired target gene, and Cas9 (CRISPR-associated protein 9)—an …
CRISPR/Cas9 therapeutics: progress and prospects
2023年1月16日 · Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating …
Past, present, and future of CRISPR genome editing technologies
2024年2月29日 · In this Review, we discuss the current state of CRISPR gene editing technologies in both research and therapy, highlighting limitations that constrain them and the …
CRISPR technologies for genome, epigenome and transcriptome editing …
2024年2月2日 · Engineered Cas variants offer diverse capabilities such as base editing, prime editing, gene insertion and gene regulation, thereby providing a panoply of tools for the …
CRISPR-Cas guides the future of genetic engineering | Science
2018年8月31日 · We describe the basic mechanisms that set the CRISPR-Cas toolkit apart from other programmable gene-editing technologies, highlighting the diverse and naturally evolved …
Mechanism and Applications of CRISPR/Cas-9-Mediated Genome Editing
CRISPR/Cas-9 gene editing is adopted from acquired immunity in prokaryotes and consists of two elements: guide RNA used to locate (bind) the target DNA to be edited and Cas-9, a protein …
Applications of CRISPR-Cas9 as an Advanced Genome Editing …
The clustered regularly interspaced short palindromic repeats associated protein 9 (CRISPR-Cas9) genome editing system has been identified as one of the most useful biological tools in …
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