Cytochrome P450 1A2 (abbreviated CYP1A2), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the human body. [5] In …

2007年11月1日 · The importance of CYP1A2 for druginteractions has been increasing overthe past decade due to the growingnumber of drugs metabolized by thisenzyme. 1 Drugs …

2021年10月1日 · ~ CYP1A2 is a phase I detoxification enzyme that breaks down caffeine as well as several other important toxins such as aflatoxin B1 from mold. ~CYP1A2 also plays a role …

2023年8月1日 · What is CYP1A2? CYP1A2 is part of the drug-metabolizing enzyme family, known as cytochrome P450. CYP1A2 plays an important role in the metabolism of several …

Given the predominant role of CYP1A2 in activation of toxic xenobiotics compared with its metabolism of prescription drugs, there are many epidemiological reports examining the role of …

2021年9月9日 · What is CYP1A2? CYP1A2 is an important detox enzyme that breaks down toxic chemicals, drugs, hormones, and other products of metabolism in order to eliminate them from …

2024年12月24日 · CYP1A2 (Cytochrome P450 Family 1 Subfamily A Member 2) is a Protein Coding gene. Diseases associated with CYP1A2 include Drug Metabolism, Poor, Cyp2c19 …

CYP1A2 is the major hepatic isoform of the human CYP1A subfamily (Shimada et al., 1994). Studies suggest negligible to no detectible CYP1A2 mRNA or protein expression/activity …

CYP1A2 gene is implicated in paranoid schizophrenia; Incubation of racemic and nonracemic methadone with CYP3A4 revealed no stereoselectivity for the transformation to EDDP, …

2024年4月25日 · CYP1A2 polymorphisms modify the association of habitual coffee consumption with appetite, macronutrient intake, and body mass index: results from an observational cohort …