Cancer stem cell - Wikipedia
Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample.
Cancer stem cells: advances in knowledge and implications for cancer …
2024年7月5日 · Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor...
Stem cells and cancer | Harvard Stem Cell Institute (HSCI)
Lurking somewhere within every tumor, some say, are a few stem cells that have lost their genetic marbles, so to speak - continuously supplying a malignant mass with cancerous cells. Stem cells are key to our normal development and health from conception through adulthood.
What Are Cancer Stem Cells? - Verywell Health
2023年8月20日 · Cancer stem cells are a small subpopulation of cells found within tumors that are tumorigenic, meaning they can create a cancerous tumor. Self-renewal and the ability to differentiate into diverse cell types are hallmark features of cancer stem cells.
Cancer Stem Cell - an overview | ScienceDirect Topics
The term cancer stem cell (CSC) is an operational term used to describe the small percentage of cells within a solid tumor capable of unregulated self-renewal, leading to continued tumor growth, as well as of the generation of partially differentiated progenitor cells [1–3].
Cancer stem cells - Latest research and news - Nature
2024年11月8日 · Cancer stem cells are rare immortal cells within a tumour that can both self-renew by dividing and give rise to many cell types that constitute the tumour, and can therefore form...
Clinical and Therapeutic Implications of Cancer Stem Cells
2019年6月5日 · Normal stem cells and their cancer stem-cell counterparts protect themselves from toxins and genotoxic stress through multiple mechanisms, including increased expression of DNA-repair...
Hallmarks of cancer stemness: Cell Stem Cell - Cell Press
2024年5月2日 · Cancer stemness, regarded as a crucial factor in tumor development, has been recognized to involve a plastic cellular state influenced by dynamic interactions between cancer stem cells (CSCs) and their niche. Herein, we provide a summary of the defining and emerging hallmarks of CSCs and/or cancer stemness.
Cancer Stem Cells - PMC
Cancer Stem Cells (CSCs) are a small subpopulation of cells within tumors with capabilities of self-renewal, differentiation, and tumorigenicity when transplanted into an animal host. A number of cell surface markers such as CD44, CD24, and CD133 ...
Stem cells, cancer, and cancer stem cells - Nature
2001年11月1日 · In particular, we focus on three aspects of the relationship between stem cells and tumour cells: first, the similarities in the mechanisms that regulate self-renewal of normal stem cells...