冷吡啉相关周期性综合征（CAPS） - 知乎专栏
冷吡啉相关周期性综合征（cryo-pyrin-associated periodic syndromes，CAPS）也称为冷炎素病（cryopyrinopathy），一组罕见的自身炎症性疾病，包括3种疾病：家族性寒冷性自身炎症综合征（familial cold autoinflammatory syndrome，FCAS）、Muckle-Wells综合征（Muckle-Wells syndrome，MWS ...
Cryopyrin-associated periodic syndrome - Wikipedia
Cryopyrin-associated periodic syndrome (CAPS) is a group of rare, heterogeneous autoinflammatory disease characterized by interleukin 1β-mediated systemic inflammation and clinical symptoms involving skin, joints, central nervous system, and eyes.
Diagnosis and Management of the Cryopyrin-Associated Periodic Syndromes ...
The cryopyrin-associated periodic syndromes (CAPS) are usually caused by heterozygous NLRP3 gene variants, resulting in excessive inflammasome activation with subsequent overproduction of interleukin (IL)-1β. The CAPS spectrum includes …
Cryopyrin-associated periodic syndromes - MedlinePlus
Cryopyrin-associated periodic syndromes (CAPS) are a group of conditions that have overlapping signs and symptoms and the same genetic cause. The group includes three conditions known as familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS), and neonatal-onset multisystem inflammatory disorder (NOMID).
Cryopyrin-associated periodic syndromes (cryopyrinopathies, …
Cryopyrin-associated periodic syndrome or syndromes (CAPS), also known as cryopyrinopathies, are genetic autoinflammatory syndromes defined by ‘gain-of-function’ mutations affecting the cryopyrin protein. Three distinct clinical syndromes are recognised within CAPS. The mildest form is FCAS, and the most severe form, NOMID/CINCA, is often fatal.
遗传性的cryopyrin-相关性周期性综合征（Cryopyrin病） - 遗传性的cryopyrin-相关性周期性综合征（Cryopyrin ...
遗传性冷热蛋白相关周期性综合征（CAPS）代表了一系列临床上重叠的自身炎症性疾病。 冷嘧啶活性增强，引发从NLRP3 炎症小体中释放IL-1beta增加，导致发炎和发热。 家族性寒冷性自身炎症综合征 (FCAS) 通常会引起寒冷诱发的荨麻疹，并伴有发烧、结膜炎，有时还会出现关节痛。 疾病发生于生后第一年。 Muckle-Wells综合征（MWS） 会引起间歇性发热、荨麻疹、关节痛和进行性感音神经性听力损失;25%的患者发生肾淀粉样变性。 除了发热和迁移性荨麻疹之外，新生儿 …
Cryopyrin-associated periodic syndrome | About the Disease
Cryopyrin associated periodic syndrome (CAPS) defines a group of autoinflammatory diseases, characterized by recurrent episodes of systemic inflammatory attacks in the absence of infection or autoimmune disease.
Cryopyrin-associated periodic syndromes: diagnosis and management
2012年4月1日 · Cryopyrin-associated periodic syndromes (CAPS) are a group of rare autoinflammatory disorders; many cases of CAPS are caused by mutations in the NLRP3 gene. In these conditions, interleukin (IL)-1 is overproduced, and this overproduction plays a major role in disease onset and progression.
Hereditary Cryopyrin-Associated Periodic Syndromes (Cryopyrinopathies)
The hereditary cryopyrin-associated periodic syndromes are a group of autosomal dominant autoinflammatory conditions characterized by recurrent episodes of fever and inflammatory symptoms; they include familial cold autoinflammatory syndrome, Muckle-Wells syndrome, and neonatal-onset multisystem autoinflammatory disease.
Cryopyrin-associated periodic syndromes and related disorders
2023年2月6日 · Three clinically overlapping interleukin (IL) 1-associated autoinflammatory disorders are known collectively as the cryopyrin-associated periodic syndromes (CAPS) or cryopyrinopathies: familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), and neonatal-onset multisystem inflammatory disorder (NOMID, also known as chronic ...