Cumulus oophorus - Wikipedia
The cumulus oophorus (discus proligerus) is a cluster of cells that surround the oocyte both in the ovarian follicle and after ovulation. In the antral follicle, it may be regarded as an extension of the membrana granulosa. The innermost layer of these cells is the corona radiata. [1]
The Function of Cumulus Cells in Oocyte Growth and Maturation …
In a good physical condition of the intrafollicular environment, cumulus cells (CCs) surrounding the oocyte, help the ability of oocyte maturation [1]. Understanding how CCs impact oocyte …
The Function of Cumulus Cells in Oocyte Growth and Maturation …
2021年9月2日 · Cumulus cells (CCs) originating from undifferentiated granulosa cells (GCs) differentiate in mural granulosa cells (MGCs) and CCs during antrum formation in the follicle by the distribution of location. CCs are supporting cells of the oocyte that protect the oocyte from the microenvironment, which h …
CEF中心科普 | 卵母细胞和体细胞的双向交流 - 知乎
Cumulus expansion denotes a grade III oocyte, the optimal stage for fertilization (2). During expansion, cumulus cells secrete a hyaluronic acid-rich matrix that binds the oocyte and cumulus together, facilitates follicular extrusion and oviductal fimbrial capture, and allows sperm penetration and fertilization (3).
Cumulus Cell - an overview | ScienceDirect Topics
Cumulus cells (CCs) are highly specialized ovarian somatic cells that support the growth, development, and maturation of the oocyte.
Redox Biology of Human Cumulus Cells: Basic Concepts, Impact …
2020年3月10日 · The cumulus cells capture glucose from the follicle microenvironment and process it through glycolysis, generating pyruvate that the oocyte will metabolize through the TAC+OXPHOS, producing biomolecules, energy (ATP), and ROS.
Oocyte-cumulus cells crosstalk: New comparative insights
2023年7月15日 · The cumulus cells connecting with the oocyte have trans-zonal cytoplasmic projections which, penetrating the zona pellucida, form the cumulus-oocyte complex. The connections through gap junctions allow the transfer of small molecules between oocyte and cumulus cells, such as ions, metabolites, and amino acids necessary for oocyte growth, as ...
Transcriptomics of cumulus cells – a window into oocyte …
2020年8月12日 · Cumulus cells (CC) provide somatic support to the maturing oocyte, and together they comprise the functional unit known as Cumulus-Oocyte-Complex (COC) [1,2,3,4]. Understanding oocyte maturation and associated pathologies can help improve fertility treatments, as well as culture media conditions in the lab.
human oocyte and cumulus cells relationship: new insights from …
2010年4月29日 · It is widely recognized that bi-directional communication exists between the human oocyte and cumulus cells (CCs) which is essential for the production of competent oocytes. CCs originate from granulosa cells (GCs) which differentiate into mural GCs and CCs during follicular antrum formation.
The Function of Cumulus Cells in Oocyte Growth and Maturation …
2021年9月2日 · CCs are supporting cells of the oocyte that protect the oocyte from the microenvironment, which helps oocyte growth and maturation in the follicles. Bi-directional communications between an...
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