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  1. Insights about clinically approved and Preclinically investigated …

    • Since the early research efforts focusing on bioactive marine substances such as spongouridine, from the marine sponge Cryptotethya crypta, marine natural products (MNPs) have arisen as a robust and sustaina… 展开

    Highlights

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    Marine natural products provide a robust platform for medications.
    ••… 展开

    ScienceDirect
    1. Introduction

    Naturally occurring compounds are broadly distributed worldwide and broadly present in natural sources, like microorganisms, marine organisms, and plants (Atanasov et al., 2015). Over t… 展开

    ScienceDirect
    2. Collection of marine organism samples (sampling techniques)

    Due to the challenging geographical distribution of marine organisms in deeper water, the difficulties in collection of marine organism samples from the oceanic environment is c… 展开

    ScienceDirect
    3. Extraction, isolation, purification, and identification protocols of MNPs

    •i)
    Extraction, isolation, and purification of MNPs
    The formulation of models for chemical and biological analys… 展开

    ScienceDirect
    4. Chemical classification of MNPs

    4.1. Alkaloids
    Alkaloidal compounds are extremely varied category of broadly disseminated cyclic molecules including basic nitrogen in a negative oxidatio… 展开

    ScienceDirect
     
  1. Pharmaceuticals from Marine Sources: Past, Present and Future

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  7. Marine-Derived Anticancer Agents: Clinical Benefits, Innovative ...

  8. An Overview on Marine Sponge-Symbiotic Bacteria as …

    2017年9月21日 · A large number of highly active anti-cancer compounds have been isolated from marine invertebrates, including eleutherobin (Eleutherobia corals), sarcodictyin (Stolonigeran coral) , cytarabine (sponge-Tectitethya …

  9. Marine sponge aquaculture towards drug development: An …

  10. Radiosensitization by Marine Sponge Agelas sp.

    2018年4月20日 · For example, cytarabine, a synthetic pyrimidine nucleoside originally isolated from the Caribbean sponge Tethya crypta has been approved for leukaemia.