Developmental progression continues during embryonic diapause …
2024年3月5日 · Embryonic diapause in mammals is a temporary developmental delay occurring at the blastocyst stage. In contrast to other diapausing species displaying a full arrest, the blastocyst of the...
The enigma of embryonic diapause - The Company of Biologists
2017年9月15日 · Embryonic diapause – a period of embryonic suspension at the blastocyst stage – is a fascinating phenomenon that occurs in over 130 species of mammals, ranging from bears and badgers to mice and marsupials. It might even occur in humans. During diapause, there is minimal cell division and greatly reduced metabolism, and development is put on hold.
Under Arrest: The Embryo in Diapause - Cell Press
2020年1月27日 · Embryonic diapause is the reversible arrest in development of mammalian embryos at the blastocyst stage. In this issue of Developmental Cell, Hussein et al. reveal that alternative splicing of Lkb1 is essential for diapause to persist and find the elevation of glycolytic and lipolytic pathways that were previously considered dormant.
Mechanisms of animal diapause: recent developments from …
2016年6月1日 · Mechanistic investigations of metabolic arrest and mitochondrial bioenergetics during diapause can be addressed particularly well with embryos of the brine shrimp that display the most profound degree of metabolic depression ever measured during diapause.
Embryonic Diapause Is Conserved across Mammals | PLOS ONE
2012年3月12日 · Embryonic diapause (ED) is a temporary arrest of embryo development and is characterized by delayed implantation in the uterus. ED occurs in blastocysts of less than 2% of mammalian species, including the mouse (Mus musculus).
Program freezing of diapausing embryos in the mouse
2024年3月15日 · Embryonal diapause is a characteristic feature of about 130 mammalian species. However, very few studies have addressed cryopreservation of diapausing embryos. This work is aimed to apply program freezing to blastocysts obtained from CD1 mice, which were at diapause state after ovariectomy and the subsequent hormonal therapy.
Embryonic diapause in humans: time to consider?
2013年9月17日 · When a competent blastocyst stage embryo finds itself in an unreceptive uterus, it delays development. In around one hundred species representing various orders, this delay is known to be reversible, but this phenomenon - termed embryonic diapause (ED) - is not considered a general characteristic of all mammals.
Diapause: Delaying the Developmental Clock in Response to a …
2013年1月1日 · Diapause can be triggered in embryos by blocking developmental growth. Some species undergo diapause as early embryos, while others enter diapause as pharate first instar larvae (“hatch-ready” larvae) within the eggshell.
Embryonic Diapause: Advances in Understanding ... - Wiley …
2012年12月24日 · Embryonic diapause is an evolutionary strategy by which a reversible arrest in embryo development occurs. In its two forms, facultative and obligate, it assures that offspring are born when optimal maternal and environmental conditions are present to ensure maximal survival.
Embryonic Diapause and Maternal Recognition of Pregnancy in Diapausing ...
Embryonic diapause is a period of suspended animation of the mammalian embryo at the blastocyst stage. Importantly, the uterus is also quiescent, and it is clear that there is a great deal of crosstalk between blastocyst at the entry into diapause, the maintenance of diapause and the reactivation from diapause.