Diterpene - Wikipedia
Diterpenes are a class of terpenes composed of four isoprene units, often with the molecular formula C 20 H 32. They are biosynthesized by plants, animals and fungi via the HMG-CoA reductase pathway, with geranylgeranyl pyrophosphate being a primary intermediate.
What’s the healthiest way to brew coffee? - Harvard Health
2020年7月1日 · Unfiltered coffee contains diterpenes, compounds that can raise cholesterol, and researchers say a cup of unfiltered coffee contains 30 times more diterpenes than a cup of filtered coffee.
Diterpenes from coffee beans decrease serum levels of ... - PubMed
Coffee diterpenes are among the few dietary exceptions shown to influence serum lipoprotein(a) levels. However, the Lp(a)-reducing potency of coffee diterpenes may subside in the long run, and their adverse side effects preclude their use as lipoprotein(a)-reducing agents.
An Overview of Biotransformation and Toxicity of Diterpenes
This review presents an overview of biotransformation processes of diterpenes carried out by microorganisms, plant cell cultures, animal and human liver microsomes, and rats, chickens, and swine in vivo and highlights the main enzymatic reactions involved in these processes and the role of diterpenes that may be effectively exploited by other ...
Cafestol and Kahweol: A Review on Their Bioactivities and ...
Cafestol and kahweol are natural diterpenes extracted from coffee beans. In addition to the effect of raising serum lipid, in vitro and in vivo experimental results have revealed that the two diterpenes demonstrate multiple potential pharmacological ...
The Therapeutic Potential of Rosemary (Rosmarinus officinalis ...
The most important diterpenes in terms of biological significance of the rosemary however remain to be carnosic acid (7) and carnosol (8) which are most abundant (~5% the dry weight) and shown to account for over 90% of rosemary's antioxidant effects [48, 62].
Diterpene - an overview | ScienceDirect Topics
Diterpenes are a group of terpenoids commonly found in terrestrial and marine organisms, characterized by a C-20 backbone formed by different combinations of isoprene units. They exhibit a wide range of biological activities such as antifungal, cytotoxic, antioxidant, and potential chemopreventive effects.
Diterpenes for Therapeutic Use - SpringerLink
2013年1月1日 · Diterpenes are a structurally diverse class of C 20 natural compounds, widely distributed in nature and originating by condensation of four isoprene units derived from mevalonate or deoxyxylulose phosphate pathways. The latter, recently discovered, originates the diterpene compounds in plants.
Diterpene - an overview | ScienceDirect Topics
Diterpenes are a diverse group of structurally complex natural products with a wide spectrum of biological activities, including antidiabetic potential. In the last 25 years, numerous diterpenes have been investigated for antidiabetic activity, with …
Therapeutic and Medicinal Uses of Terpenes | SpringerLink
2019年11月12日 · Diterpenes have many therapeutic benefits such as antitumor, cytotoxic, and anti-inflammatory (Vasas and Hohmann 2014). They are present in anticancer drugs such as taxol, and the tumor promoter, phorbol (Vasas and Hohmann 2014).