Dopaminergic Neurons and Brain Reward Pathways - PMC
Midbrain dopaminergic (DA) neurons in the substantia nigra pars compacta and ventral tegmental area regulate extrapyramidal movement and important cognitive functions, including motivation, reward associations, and habit learning.
多巴胺能神经元 - 百度百科
多巴胺能神经元（dopaminergic neuron）含有并释放多巴胺作为神经递质的神经元。 实验资料表明，在哺乳动物各脑区的含量不同。 其中，尾核、壳核内含量最高，其次是黑质和苍白球。
Development, wiring and function of dopamine neuron subtypes
2023年1月18日 · This progress is important for further understanding the disparate physiological functions of mDA neurons and their selective vulnerability in disease, and will ultimately accelerate therapy ...
Dopaminergic pathways - Wikipedia
The transmission of dopaminergic neurons to the dorsal striatum particularly plays a role in reward and motivation while movement is influenced by the transmission of dopaminergic neurons to the substantia nigra.
Dopamine in Health and Disease: Much More Than a …
2021年1月22日 · In the central nervous system, it is produced and released by the so-called dopaminergic neurons, which are found in different brain areas but are especially abundant in the substantia nigra.
Dopamine: The Neuromodulator of Long-Term Synaptic Plasticity, …
2021年3月26日 · Dysfunction in dopaminergic transmission is recognized as a core alteration in several devastating neurological and psychiatric disorders, including Parkinson’s disease (PD), schizophrenia, bipolar disorder, attention deficit hyperactivity disorder (ADHD) and addiction.
Dopaminergic Neuron - an overview | ScienceDirect Topics
Dopaminergic neurons are large neurons that reside mostly within the pars compacta of the substantia nigra and in the ventral tegmental area (van Domburg & ten Donkelaar, 1991). A distinctive feature of these cells is the presence of a pigment, neuromelanin , in compact granules in the cytoplasm.
Dopamine and the Dopaminergic Systems of the Brain
The mesocortical and mesolimbic dopaminergic neurons are involved in cognitive and emotive functions and in the pathophysiology of various forms of psychosis. These dopaminergic systems are widely used to explain the mode of action of antipsychotic drugs and chemicals inducing drug abuse.
Dopaminergic cell groups - Wikipedia
Dopaminergic cell groups, DA cell groups, or dopaminergic nuclei are collections of neurons in the central nervous system that synthesize the neurotransmitter dopamine. [1] In the 1960s, dopaminergic neurons or dopamine neurons were first identified and named by Annica Dahlström and Kjell Fuxe , who used histochemical fluorescence . [ 2 ]
Dopamine: Current Biology - Cell Press
2022年8月8日 · Most dopamine neurons display auto-regulatory control by expressing pre-synaptic D2Rs in both the axonal and somatodendritic compartments, meaning that when a neuron releases dopamine it also inhibits itself.