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Fetal hemoglobin - Wikipedia
Fetal hemoglobin, or foetal haemoglobin (also hemoglobin F, HbF, or α2γ2) is the main oxygen carrier protein in the human fetus. Hemoglobin F is found in fetal red blood cells, and is involved in transporting oxygen from the mother's bloodstream to organs and tissues in the fetus. It is produced at around 6 weeks of … 展开
Hemoglobin F, like adult hemoglobin (hemoglobin A and hemoglobin A2), has four subunits or chains. Each subunit contains a heme group with an iron element which is key in … 展开
During pregnancy, the mother's circulatory system delivers oxygen and nutrients to the fetus and carries away nutrient-depleted blood enriched … 展开
During pregnancy
There is a significant increase in hemoglobin F levels during early pregnancy. However, it's … 展开During the first 3 months of pregnancy, the main form of hemoglobin in the embryo/fetus is embryonic hemoglobin, which has 3 variants depending on the types of subunits it … 展开
Factors affecting oxygen affinity
The four hemes, which are the oxygen-binding parts of hemoglobin, are similar between hemoglobin F and other types of hemoglobin, including hemoglobin A. Thus, the key feature that allows hemoglobin F to bind … 展开F-cells are the subpopulation of red blood cells that contain hemoglobin F, in amongst other types of hemoglobin. While common in fetuses, in normal adults, only around 3-7% of red blood … 展开
Treatment of sickle-cell disease
The discovery that hemoglobin F alleviated the symptoms of sickle cell disease occurred in 1948. … 展开CC-BY-SA 许可证中的维基百科文本 Physiology, Fetal Hemoglobin - StatPearls - NCBI …
2023年3月20日 · The evolution of hemoglobin follows gene mutations, such as gene duplication, gene conversion, and translocation of genes in ancient …
- 作者: Daniel P. Kaufman, Jasmin Khattar, Sarah L. Lappin
- 已发布: 2023/03/20
- Publish Year: 2019
Molecule of the Month: Fetal Hemoglobin - RCSB: PDB …
Each installment includes an introduction to the structure and function of the molecule, a discussion of the relevance of the molecule to human health and welfare, and suggestions for how visitors might view these structures and …
Embryonic and Fetal Human Hemoglobins: Structures, Oxygen
Comparison Between the Structure of Fetal and Adult Hemogloblin
Embryonic and Fetal Human Hemoglobins: Structures, Oxygen …
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2021年5月7日 · Structure of HbF. HbF is present in fetal life; however, its production ceases in the period just after the child is born.
Fetal Hemoglobin - an overview | ScienceDirect Topics