Galactosamine is a hexosamine derived from galactose with the molecular formula C 6 H 13 NO 5. This amino sugar is a constituent of some glycoprotein hormones such as follicle-stimulating hormone (FSH) and luteinizing hormone (LH).

半乳糖胺 （galactosamine），一种 己糖胺。 D -半乳糖胺 与 D -葡萄糖胺 是4- 差向异构体，常用的化学系统名是2-氨基-2-脱氧- D -半乳糖（2-amino-2-deoxy- D -galactose）。 在自然界其作为构成动物细胞和组织支持物质的糖蛋白和蛋白多糖的组成糖（以 N -乙酰半乳糖胺 的形态）是广泛存 …

Galactosamine is an amino derivative of the sugar galactose, which is a major component of glycoproteins, an essential part of living cells. This amino sugar is also a constituent of some glycoprotein hormones such as follicle-stimulating hormone and luteinizing hormone.

Galactosamine (GalN) is an established experimental hepatotoxicant, first reported in the 1970s. It induces hepatitis characterized by neutrophilic infiltration, which ultimately leads to death by fulminant hepatic failure.

D- (+)-氨基半乳糖，也称为D-软骨糖胺（D-Chondrosamine），一种非常强效的肝脏RNA合成抑制剂，能够增强多形核白细胞对肝内皮细胞的粘附性，以及诱导超氧化物生成。 D- (+)-氨基半乳糖还能诱发肝损伤，进而导致巨噬细胞浸润。 本品D- (+)-氨基半乳糖的盐酸盐形式提供，CAS NO. 1772-03-8，常与脂多糖（LPS，货号：MS0801-10MG）联合使用以建立急性肝衰竭动物模型，从而来筛选有价值的临床新药。 2. Lipopolysaccharides（脂多糖，简称LPS） LPS，革兰氏阴 …

It is a D-galactosamine and a primary amino compound. It is functionally related to a D-galactopyranose. It is a conjugate base of a 2-ammonio-2-deoxy-D-galactopyranose. D-Galactosamine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).

Galactosamine is a model hepatotoxicant, induces hepatitis characterized by neutrophilic infiltration, and kills the animal by fulminant hepatic failure. Galactosamine induces liver injury by interfering with the uridine pool in the cell, which is essential for RNA and protein synthesis.

D(+)-Galactosamine hydrochloride | C6H14ClNO5 | CID 2723866 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

galactosamine，英语单词，主要用作名词，作名词时译为“ [有化] 半乳糖胺”。 [1] To establish the standard model of endotoxins shock of mice sensitized with D-galactosamine. 建立D -氨基半乳糖敏化小鼠内毒素休克的规范化模型。 Objective to observe the effect of Jiangzhi Ninggan capsule on acute hepatic injury induced by D-galactosamine (D-Gal) in mice. 目的：观察降脂宁肝胶囊对大鼠脂肪肝的治疗作用并初步探讨其作用机制。

D-半乳糖 胺（D-gal）是一种肝细胞磷酸 尿嘧啶核苷 干扰剂，可造成肝弥漫性坏死和炎症，与临床 病毒性肝炎 的肝脏病理变化相似。 大剂量可造成爆发性肝衰竭模型，反复多次给药则可造成 肝纤维化 、肝硬化等慢性肝损伤以及癌变。 其中毒机理是半乳糖胺进入体内后，能竞争性捕捉UTP生成二磷酸尿苷半乳糖 (UDP-galactose, UDP-gal)，使磷酸尿苷耗竭，使依赖其生物合成的核酸、糖蛋白、脂糖等物质合成受抑制，限制了细胞器及酶的生成和补充，细胞器受损、膜损害致使钙 …