Which Is Best? Indole-3-Carbinol Vs. DIM - Life Extension
I3C vs DIM. Recently, negative statements have surfaced about Indole-3-carbinol, a phytochemical found in cruciferous vegetables that has shown great potential in the prevention of cancer. Here, we set the record straight. Scientifically reviewed by: Dr. Gary Gonzalez, MD, in October 2024. Written by: Life Extension Editorial Staff.
Broccoli extracts – DIM, SGS & I3C – which one do I use?
2020年11月5日 · Indole 3 Carbinol or I3C for short, is a compound found in cruciferous vegetables like broccoli, broccoli sprouts, cabbage, brussels sprouts, kale and cauliflower. It breaks down into the metabolites Diindolylmethane (DIM) and Sulforaphane Glucosinolate (SGS).
DIM Supplements: Benefits, Side Effects, and Dosage - Healthline
2023年3月17日 · When you eat cruciferous vegetables, your stomach acid breaks down a compound called indole-3-carbinol to produce a new compound called DIM (3). Intriguingly, observational studies associate...
DIM vs I3C: Which One Is Better for Estrogen Dominance?
2024年9月9日 · Diindolylmethane (DIM) and indole-3-carbinol (I3C) are common natural options for estrogen dominance and hormonal imbalance. They are both derived from cruciferous vegetables. So what’s the difference between the two?
3,3′-Diindolylmethane and indole-3-carbinol: potential …
Indole-3-carbinol (I3C) and 3,3′-diindolylmethane (DIM) are heterocyclic and bioactive chemicals found in cruciferous vegetables like broccoli, cauliflower, cabbage, and brussels sprouts. They are synthesized after glycolysis from the glucosinolate structure.
What’s the difference between DIM and I3C? - Thorne
2022年6月5日 · One of the main differences between I3C and DIM lies in the stability of the molecules. I3C is relatively unstable – meaning it quickly converts to DIM and other substances after it’s in your stomach. DIM, on the other hand, is quite stable.
Indole-3-Carbinol: Occurrence, Health-Beneficial Properties, and ...
2023年3月27日 · Both I3C and DIM alter multiple signaling pathways and related molecules controlling diverse cellular events, including oxidation, inflammation, proliferation, differentiation, apoptosis, angiogenesis, and immunity.
Science Review: Indole-3-carbinol (I3C) and 3,3’-diindolylmethane (DIM)
DIM. In healthy subjects, single-dose oral administration of absorption-enhanced DIM (50-300 mg) demonstrated a linear increase of DIM in plasma. The single 200 mg produced a peak plasma DIM concentration of 104 ng/mL and was no longer detectable after 24 hours. 23; Multidose pharmacokinetic studies of absorption-enhanced DIM are lacking.
I3C & DIM: Adjunctive Therapy for Breast Cancer Patients on Tamoxifen
2021年12月16日 · Both I3C and its derivative, DIM, have demonstrated positive outcomes for breast cancer in breast cancer cell-line studies and clinical studies.
Indole-3-Carbinol - Memorial Sloan Kettering Cancer Center
2023年8月2日 · Natural indoles, indole-3-carbinol (I3C) and 3,3’-diindolylmethane (DIM), attenuate staphylococcal enterotoxin B-mediated liver injury by downregulating miR-31 expression and promoting caspase-2-mediated apoptosis.