Pegylated interferon: the who, why, and how - American Society …
2024年12月6日 · Interferon alpha (IFN-α) is a fascinating molecule with many biological properties yet to be fully understood. Among these properties, several have demonstrated usefulness for targeting malignant cells, including hematopoietic cells …
Pegylated interferon - Wikipedia
Pegylated interferon (PEG-IFN) is a class of medication that includes three different drugs as of 2012: [1] In these formulations, Polyethylene glycol (PEG) is added to make interferon last longer in the body. [3] . They are used to treat both hepatitis B, [4] hepatitis C …
Pegylated interferon alfa-2a for polycythemia vera or essential ...
2019年10月31日 · A phase II trial of pegylated interferon α-2b therapy for polycythemia vera and essential thrombocythemia: feasibility, clinical and biologic effects, and impact on quality of life.
Pegylated interferon: the who, why, and how - PubMed
2024年12月6日 · Interferon alpha (IFN-α) is a fascinating molecule with many biological properties yet to be fully understood. Among these properties, several have demonstrated usefulness for targeting malignant cells, including hematopoietic cells …
PharmGKB summary: peginterferon-α pathway - PMC
Pegylated interferon-α (peginterferon-α or PEG-IFN-α) is an antiviral and immunoregulatory drug that has served as the foundation for the treatment of hepatitis C virus (HCV) infection for more than two decades.
What the Infectious Disease Physician Needs to Know About Pegylated …
This review summarizes the relevant issues with pegylated interferon and ribavirin, with a particular focus on side effects profile and management, as well as their continued role in therapy given the emergence of interferon-free regimens.
Pegylated Interferon - an overview | ScienceDirect Topics
Interferon (IFN) α, or combination therapy of pegylated (PEG)-IFN and ribavirin, is the standard therapy for chronic viral hepatitis C (HCV). IFN-ß1 alpha is also another kind of interferon which is commonly used in the treatment of multiple sclerosis.
Peginterferon - an overview | ScienceDirect Topics
Pegylated interferon is a first-line treatment for chronic hepatitis B. Finite treatment duration, absence of drug resistance, delayed response, and higher hepatitis B surface antigen loss than nucleos(t)ides analog therapy are the advantages of pegylated interferon-alpha treatment.
Pegylated Interferon - an overview | ScienceDirect Topics
PEGASYS, pegylated interferon alfa-2a, is a covalent conjugate of human interferon alfa-2a with a single branched bis-monomethoxy-polyethylene glycol (PEG) chain (approximate MW=40,000). From: Encyclopedia of Hormones, 2003
Pegylated interferons - PubMed
Pegylated IFNs with ribavirin are the standard of care for treating patients with chronic HCV who have not been treated previously. In summary, pegylated IFNs have a longer half-life, reduced immunogenicity, better pharmacokinetics, and enhanced …