Pluripotent - Definition and Examples - Biology Online Dictionary
2022年2月16日 · Pluripotent cells are the embryonic stem cells that have the unlimited capacity to divide, self-renew and differentiate into cells of early primary germ cell layers, namely mesoderm, endoderm, and ectoderm.
Stem Cell Basics | STEM Cell Information - National Institutes of Health
There are several main categories: the “pluripotent” stem cells (embryonic stem cells and induced pluripotent stem cells) and nonembryonic or somatic stem cells (commonly called “adult” stem cells). Pluripotent stem cells have the ability to differentiate into all of the cells of the adult body.
Induced pluripotent stem cells (iPSCs): molecular mechanisms of ...
2024年4月26日 · In this review, we outline key developments in the iPSC field and highlight the immense versatility of the iPSC technology for in vitro modeling and therapeutic applications. We begin by discussing...
Cell Potency: Totipotent vs Pluripotent vs Multipotent Stem Cells
2023年12月18日 · Totipotent (omnipotent) stem cells can give rise to any of the 220 cell types found in an embryo as well as extra-embryonic cells (placenta). Pluripotent stem cells can give rise to all cell types of the body (but not the placenta). Multipotent stem cells can develop into a limited number of cell types in a particular lineage.
induced pluripotent stem cell - Encyclopedia Britannica
2024年10月27日 · induced pluripotent stem cell (iPS cell), immature cell that is generated from an adult (mature) cell and that has regained the capacity to differentiate into any type of cell in the body. Induced pluripotent stem cells (iPS cells) differ from embryonic stem cells (ES cells), which form the inner cell mass of an embryo but also are pluripotent ...
Stem cells: past, present, and future - Stem Cell Research
2019年2月26日 · Pluripotent stem cells (PSCs) form cells of all germ layers but not extraembryonic structures, such as the placenta. Embryonic stem cells (ESCs) are an example. ESCs are derived from the inner cell mass of preimplantation embryos. Another example is induced pluripotent stem cells (iPSCs) derived from the epiblast layer of implanted embryos.
Defining Human Pluripotency: Cell Stem Cell - Cell Press
2019年7月3日 · Here, we review pluripotency in human cells with respect to four different aspects: (1) embryonic development, (2) transcriptomes of pluripotent cell stages, (3) genes and pathways that reprogram somatic cells into pluripotent stem cells, and finally (4) the recent identification of the human pluripotent stem cell essentialome.
Pluripotent stem cells - Latest research and news | Nature
2024年11月27日 · Pluripotent stem cells are cells that have the capacity to self-renew by dividing and to develop into the three primary germ cell layers of the early embryo and therefore into all cells...
Induced pluripotent stem cells | UCLA BSCRC
Induced pluripotent stem cells are derived from skin or blood cells that have been reprogrammed back into an embryonic-like pluripotent state that enables the development of an unlimited source of any type of human cell needed for therapeutic purposes.
Hallmarks of totipotent and pluripotent stem cell states - Cell Press
2024年2月20日 · While artificially maintained, the dynamic totipotent and pluripotent stem cells offer an invaluable resource for studying early mammalian development, focusing on cell potency and cell plasticity, environmental and experimental perturbations, and in vitro state transitions. These cells also hold great potential to transform the fields of ...