Pyrazolone is 5-membered heterocycle containing two adjacent nitrogen atoms. It can be viewed as a derivative of pyrazole possessing an additional carbonyl (C=O) group. Compounds containing this functional group are useful commercially in analgesics and dyes.

2024年8月13日 · By binding to cell membrane proteins, pyrazolone-bearing dyes enabled precise cell tracking in vitro (>96 h) and in vivo (>21 days) without interfering with the protein function or causing cell death.

Pyrazolone | C3H2N2O | CID 11513733 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

吡唑酮类 (Pyrazolon Derivatives)解热镇痛药是一组以保泰松 (Phenylbutazone)为代表的药物，属于非甾体抗炎药 (NSAID)。 早在1884年，安替比林即已合成问世，被用作解热镇痛和抗炎药，几年后又合成氨基比林。 因此在19世纪末阿斯匹林尚未问世以前，此两种药物已十分畅销。 此后很长一段时间没有新药，直到1948年才发现保泰松。 由于吡唑酮类药物有较严重的毒副作用，一般应用较少，在临床疼痛治疗中不占重要地位 [1]。 吡唑酮类药物是安替比林的衍生物，毒性较 …

2020年1月15日 · The pyrazolone structural motif is a critical element of drugs aimed at different biological end-points. Medicinal chemistry researches have synthesized drug-like pyrazolone candidates with several medicinal features including antimicrobial, antitumor, CNS (central nervous system) effect, anti-inflammatory activities and so on.

2023年11月6日 · Pyrazole nucleus is a rare structural stage attractive for combinatorial and medicinal chemistry. In addition, it encloses the most recent reports on a structural variation on pyrazole explaining...

2022年8月15日 · Pyrazolone, featuring a five-membered ring with nitrogen–nitrogen bond and an additional ketonic group (C=O) is considered as one of the important heterocyclic compounds owing to their widespread presence in medical chemistry [13].

Pyrazolone T | C10H8N2O6S | CID 67045 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

Pyrazole 1 is an aromatic molecule and, like its structural isomer imidazole, contains a pyrrole-like and a pyridine-like N atom, but in the 1- and 2-positions (1,2-diazole). This survey of possible structures follows the convention adopted in CHEC (1984) <1984CHEC (5)167>.

ChemicalBook 致力于为化学行业用户提供吡唑啉酮的性质、化学式、分子式、比重、密度,同时也包括吡唑啉酮的沸点、熔点、MSDS、用途、作用、毒性、价格、生产厂家、用途、上游原料、下游产品等信息。