Rhodopsin - Wikipedia
Rhodopsin, also known as visual purple, is a protein encoded by the RHO gene [5] and a G-protein-coupled receptor (GPCR). It is a light -sensitive receptor protein that triggers visual phototransduction in rods.
视紫红质 - 百度百科
视紫红质（ rhodopsin ）是 一种 结合蛋白 ，由 视黄醛 （也称网膜素，retinal）和 视蛋白 （opsin）结合而成。 视黄醛由 维生素A 氧化而形成，是维生素A的醛化合物。
Rhodopsin | Biochemistry, Photoreception & Vision | Britannica
Rhodopsin, pigment-containing sensory protein that converts light into an electrical signal. Rhodopsin is found in a wide range of organisms, from vertebrates to bacteria. In many seeing animals, including humans, it is required for vision in dim light and is located in the retina of the
Structure and activation of rhodopsin - Acta Pharmacologica …
2012年1月23日 · Rhodopsin is the first G-protein-coupled receptor (GPCR) with its three-dimensional structure solved by X-ray crystallography.
Rhodopsin - an overview | ScienceDirect Topics
Rhodopsin is the vertebrate visual protein of rod cells which is responsible for dim light vision. Rhodopsin consists of a protein chain, opsin (M r ≃ 38,000), to which a molecule of 11-cis retinal is bound. In the first event in vision, rhodopsin absorbs a photon causing a change in the structure or electronic state of the 11-cis retinal ...
G Protein–Coupled Receptor Rhodopsin - PMC - PubMed …
The rhodopsin crystal structure provides a structural basis for understanding the function of this and other G protein–coupled receptors (GPCRs). The major structural motifs observed for rhodopsin are expected to carry over to other GPCRs, and the ...
Rhodopsin: A Potential Biomarker for Neurodegenerative Diseases
2020年4月14日 · Retinal alterations have recently been associated with numerous neurodegenerative diseases. Rhodopsin is a G-protein coupled receptor found in the rod cells of the retina. As a biomarker associated with retinal thinning and degeneration, it bears potential in the early detection and monitoring of several neurodegenerative diseases.
Microbial and Animal Rhodopsins: Structures, Functions, and …
2013年12月23日 · Rhodopsin differs from diffusible ligand-activated GPCRs by its covalently linked retinal and photochemical core enabling photosensory function. 11-cis-retinal serves together with the constraints described above in highly efficient stabilization of the inactive dark state of rhodopsin.
Structure-based insights into evolution of rhodopsins
2021年6月30日 · The first high-resolution structure of fungi rhodopsin and its functional properties reveal the striking similarity of its membrane part to archaeal but not to bacterial rhodopsins.
RHO rhodopsin [Homo sapiens (human)] - Gene - NCBI
5 天之前 · Title: Identification of small-molecule allosteric modulators that act as enhancers/disrupters of rhodopsin oligomerization. Structural Basis of Arrestin Selectivity for Active Phosphorylated G Protein-Coupled Receptors.