The TSHR gene provides instructions for making a protein, known as a receptor, that attaches (binds) to a hormone called thyroid stimulating hormone (TSH). Learn about this gene and related health conditions.

The thyrotropin receptor (or TSH receptor) is a receptor (and associated protein) that responds to thyroid-stimulating hormone (also known as "thyrotropin") and stimulates the production of thyroxine (T4) and triiodothyronine (T3).

Data indicate the structural integrity of thyroid stimulating hormone receptor isoform (TSHR) and its potential binding of thyroid stimulating hormone (TSH). TSHR protein was detected on human EOM myoblasts and increasing TSHR expression during myogenic differentiation.

2017年7月24日 · The thyroid-stimulating hormone (TSH) receptor (TSHR) is a member of the glycoprotein hormone receptors (GPHRs), a sub-group of class A G protein-coupled receptors (GPCRs). TSHR and its ligand thyrotropin are of essential importance for growth and function of the thyroid gland.

2024年12月25日 · TSHR (Thyroid Stimulating Hormone Receptor) is a Protein Coding gene. Diseases associated with TSHR include Hyperthyroidism, Familial Gestational and Hypothyroidism, Congenital, Nongoitrous, 1. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling.

2022年4月13日 · The TSH receptor (TSHR) is a member of the glycoprotein hormone receptors, a subfamily of family A G protein-coupled receptors. The TSHR is of great importance for the growth and function of the thyroid gland. The TSHR and its endogenous ligand TSH ...

Thyroid stimulating hormone receptor (TSHR) plays a pivotal role in thyroid hormone metabolism. It is a major controller of thyroid cell function and growth. Mutations in TSHR may lead to several thyroid diseases, most commonly hyperthyroidism. ...

Thyroid stimulating hormone receptor (TSHR) is a receptor for thyrostimulin and thyroid stimulating hormone (TSH, also called thyrotropin) [1]. TSHR is a cell surface glycoprotein receptor and belongs to the leucine-rich repeat (LGR) …

2024年6月17日 · TSHR thyroid stimulating hormone receptor Gene ID: 7253, updated on 17-Jun-2024 Gene type: protein coding Also known as: LGR3; CHNG1; hTSHR-I. See all available tests in GTR for this gene; Go to complete Gene record for TSHR; Go to Variation Viewer for TSHR variants; Summary

Several TSHR gene mutations have been identified in people with congenital hypothyroidism, a condition characterized by abnormally low levels of thyroid hormones starting from birth.