Tetraploidy | About the Disease | GARD - Genetic and Rare …
Tetraploidy is an extremely rare chromosomal anomaly, polyploidy, when an affected individual has four copies of each chromosome, instead of two, resulting in total of 92 chromosomes in …
Tetraploidy in cancer and its possible link to aging - PMC
Tetraploidy, a condition in which a cell has four homologous sets of chromosomes, is often seen as a natural physiological condition but is also frequently seen in pathophysiological conditions …
Tetraploidy in the era of molecular karyotyping – What we need …
2013年9月1日 · Tetraploidy is a condition in which there are four complete sets of chromosomes in a single cell. In humans, this would be 92 sets of chromosomes per cell, i.e., 92,XXXX (in …
Tetraploidy - an overview | ScienceDirect Topics
Tetraploidy is an infrequent chromosomal abnormality, but triploidy occurs fairly often. Most triploid embryos miscarry in the first trimester. In approximately 20% of first-trimester …
Tetraploidy - an overview | ScienceDirect Topics
Tetraploidy refers to a rare chromosomal abnormality characterized by the presence of four sets of chromosomes instead of the usual two sets. It is often associated with multiple congenital …
Tetraploidy - Chromosomal Variation in Man - NCBI Bookshelf
Results show a maternal origin of one additional set of chromosomes most likely due to the incorporation of the polar body of meiosis I and a paternal origin of the second additional set of …
Tetraploidy causes chromosomal instability in acentriolar ... - Nature
2019年10月23日 · Tetraploidisation is considered a common event in the evolution of chromosomal instability (CIN) in cancer cells. The current model for how tetraploidy drives CIN …
The consequences of tetraploidy and aneuploidy
2008年12月1日 · Here, we review how tetraploidy can occur and describe the cellular responses to increased ploidy. Furthermore, we discuss how the specific physiological changes that are …
Tetraploidy and tumor development: Cancer Cell - Cell Press
Tetraploidy, the presence of twice the normal number of chromosomes, is an ominous state in mammalian tissues. In many human carcinomas, cells with tetraploid DNA content arise as an …
The consequences of tetraploidy and aneuploidy - PubMed
2008年12月1日 · Here, we review how tetraploidy can occur and describe the cellular responses to increased ploidy. Furthermore, we discuss how the specific physiological changes that are …