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Connexon - Wikipedia
In biology, a connexon, also known as a connexin hemichannel, is an assembly of six proteins called connexins that form the pore for a gap junction between the cytoplasm of two adjacent cells. This channel allows for bidirectional flow of ions and signaling molecules. [1]
Connexin - Wikipedia
Connexins (Cx) (TC# 1.A.24), or gap junction proteins, are structurally related transmembrane proteins that assemble to form vertebrate gap junctions. An entirely different family of proteins, the innexins, forms gap junctions in invertebrates. [1] .
Connexins in the Heart: Regulation, Function and Involvement in Cardiac ...
Connexins are a family of transmembrane proteins that play a key role in cardiac physiology. Gap junctional channels put into contact the cytoplasms of connected cardiomyocytes, allowing the existence of electrical coupling. However, in addition to this fundamental role, connexins are also involved in cardiomyocyte death and survival.
Connexins: a myriad of functions extending beyond assembly of …
2009年3月12日 · Connexins constitute a large family of trans-membrane proteins that allow intercellular communication and the transfer of ions and small signaling molecules between cells.
Connexins, connexons, and intercellular communication
Intercellular channels are formed from two oligomeric integral membrane protein assemblies, called connexons, which span two adjacent cells' plasma membranes and join in a narrow, extracellular "gap." Connexons are formed from connexins, a highly related multigene family consisting of at least 13 members.
Gap junction - Wikipedia
Gap junctions use protein complexes known as connexons to connect one cell to another. The proteins are called connexins. Gap junction proteins include the more than 26 types of connexin, and at least 12 non-connexin components that make up the gap junction complex or nexus. [4] .
Gap Junctions: Cell-Cell Channels in Animals
Two connexons join in the gap between the cells to form a gap junction channel that connects the cytoplasms of the two cells. A connexon is composed of six transmembrane proteins, called connexins (Cx), which form a multigene family.
Gap junction protein Connexin-43 is a direct transcriptional
2018年9月21日 · We show that Connexin 43 (Cx43) controls neural crest cell migration in vivo by directly regulating N-cadherin transcription. This activity requires interaction between Cx43 carboxy tail and the...
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