The lamin protein family | Genome Biology | Full Text - BioMed …
2011年12月5日 · The lamins are the major architectural proteins of the animal cell nucleus. Lamins line the inside of the nuclear membrane, where they provide a platform for the binding …
The nuclear lamins: flexibility in function - Nature
2012年12月5日 · The nuclear lamina is an important structural determinant for the nuclear envelope as a whole, and its functions include attaching chromatin domains to the nuclear …
Lamins: The backbone of the nucleocytoskeleton interface
2024年2月1日 · The nuclear lamina (NL) is a crucial component of the inner nuclear membrane (INM) and consists of lamin filaments and associated proteins. Lamins are type V intermediate …
Lamin - an overview | ScienceDirect Topics
Lamins are nuclear intermediate filament proteins and are the principal component of the nuclear lamina, a meshwork of proteins residing just inside the inner nuclear membrane (INM).
Lamins at a glance - PMC
Lamins, the major components of the nuclear lamina, have gained rapidly increasing interest over the past decade as lamin mutations were found to cause numerous devastating diseases.
The laminin family - PMC
Laminins are large molecular weight glycoproteins constituted by the assembly of three disulfide-linked polypeptides, the α, β and γ chains. The human genome encodes 11 genetically distinct …
Nuclear Lamins: Thin Filaments with Major Functions - Cell Press
2017年9月9日 · Lamins are nuclear IFs that make a meshwork of filaments at the nuclear periphery. Each major lamin isoform forms a separate meshwork. The lamin filaments are …
Functional mechanisms and abnormalities of the nuclear lamina
2021年2月8日 · Mouse lamin A and C are derived from a single gene (Lmna) through alternative splicing, while B-type lamins are expressed from individual genomic loci (Lmnb1 and Lmnb2) …
The nuclear lamina comes of age | Nature Reviews Molecular Cell …
2005年1月1日 · The nuclear lamina is a network of lamin polymers and lamin-binding proteins that are embedded in the INM. In the nuclear interior, lamins also form stable complexes (internal …
Lamin A/C: Function in Normal and Tumor Cells - MDPI
2020年12月9日 · Lamin A/C is a nuclear protein with many functions in cells, such as maintaining a cell’s structural stability, cell motility, mechanosensing, chromosome organization, gene …
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