2014年11月13日 · Massive hemorrhage is associated with coagulopathy and high mortality. The transfusion guidelines up to 2006 recommended that resuscitation of massive hemorrhage should occur in successive steps using crystalloids, colloids, and red blood cells (RBCs) in the early phase and plasma and platelets in the late phase.

2020年11月3日 · These three factors both cause, and contribute to, acute coagulopathy of trauma/ shock (ACoTS) which leads to, and result from, major hemorrhage. They feed off one another, such that bleeding begets more bleeding.

2024年11月25日 · Massive transfusion is a treatment for massive hemorrhage. It can keep patients alive through volume and oxygen transport replacement while other methods to control bleeding sources such as surgery, interventional radiology, endoscopy, or uterine packing are carried out, and then it can replace lost blood volume to facilitate recovery and healing.

Massive bleeding is defined as the loss of more than one blood volume within 24 hours (h), 50% of the patient's total blood volume lost in less than 3h or bleeding in excess of 150ml/minute[1]. Postpartum hemorrhage is defined as blood loss greater than …

2021年9月7日 · Massive hemorrhage protocols (MHPs) are tools designed to expedite the provision of blood components based on best practices for the management of massively bleeding patients.

Massive transfusion usually is defined as the transfusion of more than 10 units of packed red blood cells (RBCs) within 24 h or a corresponding blood loss of more than 1- to 1.5-fold of the body's entire blood volume. Especially male trauma patients experience this life-threatening condition within their productive years of life.

Major haemorrhage is a leading cause of morbidity and mortality worldwide. Successful treatment requires early recognition, planned responses, readily available resources (such as blood products) and rapid access to surgery or interventional radiology.

2023年10月23日 · A clinical approach to the first 10 minutes of emergency resuscitation of a patient with Massive hemorrhage.

In this article, we review the existing evidence and provide a pragmatic framework, the 7 Ts of massive hemorrhage protocol, to guide the care of patients with life-threatening traumatic hemorrhage. Keywords: Damage control resuscitation; Massive hemorrhage protocol; Resuscitation; Trauma.

Massive hemorrhage remains a major cause of potentially preventable deaths. Better control of bleeding could improve survival rates by 10%–20%. Transfusion intervention concepts have been formulated in order to minimize acute traumatic coagulopathy.