Thiophene is a heterocyclic compound with the formula C 4 H 4 S. Consisting of a planar five-membered ring, it is aromatic as indicated by its extensive substitution reactions. It is a colorless liquid with a benzene -like odor.

Thiophene is a naturally occurring substance found in coal tar and petroleum. It is also produced industrially for use as an organic synthesis reagent and may be released to the environment through a variety of waste streams.

Thiophene, the simplest sulfur-containing aromatic compound, with molecular formula C4H4S, which closely resembles benzene in its chemical and physical properties. It occurs with benzene in coal tar, from which source it was first isolated in 1883.

Thiophene is a heterocyclic compound of particular interest in the field of organic chemistry. This cyclic molecule, sometimes referred to as thiofuran, consists of four carbon atoms and one sulfur atom in a ring structure.

Thiophene is a privileged pharmacophore in medicinal chemistry owing to its diversified biological attributes. The thiophene moiety has been ranked 4th in the US FDA drug approval of small drug molecules, with around 7 drug approvals over the last ...

In thiophene, the dipole is directed from the ring toward the heteroatom. Although thiophene is aromatic and assumed to be derived from benzene, the bond-length equivalence seen for the C–C and C–H bonds in benzene is not found here.

Thiophene was first discovered in 1882 by Victor Meyer. It is a colorless liquid with a boiling point of 84.4 °C (760 Torr) and a melting point of −38.3 °C <1983KO965>.

Thiophene is a five-membered heterocyclic compound containing a sulphur (S) atom (Gramec et al., 2014). Natural thiophenes from plants are reported to be found in many Asteraceae, especially the genus Echinops, Eclipta, Pluchea, Artemisia, Tagetes, Porophyllum, Atractylodes, Atractylodes, and Xanthium (Ibrahim et al., 2016).

2024年4月22日 · Thiophene is a liquid with a boiling point of 84 °C, found in coal tar. It occurs as a contaminant of benzene, when obtained from coal tar. fig-01. Thiophene is an electron-rich aromatic compound. Its resonance energy is approximately equal to that of pyrrole, and much higher than that of furan. It is found in nature in certain plant products ...

2011年1月1日 · The present review provides a broad view of the synthesis and properties of compounds having thiophene nucleus.